@article{mbs:/content/journal/jmm/10.1099/00222615-27-1-45, author = "Antoine, I. and Coene, M. and Cocito, C.", title = "Size and homology of the genomes of leprosy-derived corynebacteria, Mycobacterium leprae, and other corynebacteria and mycobacteria", journal= "Journal of Medical Microbiology", year = "1988", volume = "27", number = "1", pages = "45-50", doi = "https://doi.org/10.1099/00222615-27-1-45", url = "https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-27-1-45", publisher = "Microbiology Society", issn = "1473-5644", type = "Journal Article", abstract = "Summary The genomes of Mycobacterium leprae and leprosy-derived corynebacteria (LDC), which have a similar base composition of guanine + cytosine 56 mol%, have been compared with those of reference bacteria of the CMN group (genera Corynebacterium, Mycobacterium, Nocardia). Genome sizes of three LDC strains were (1.2–2.5) × 106 base pairs. DNA from four of seven LDC strains examined had homology levels >60%. Two other strains had a homology of 40% when compared with the CMN strains and one strain was distinctly different. The DNA from all seven LDC strains gave 0.3–18% hybridisation with that of M. leprae, 5–16% with reference corynebacteria, 5–12% with M. bovis, and 2–8% with Nocardia caviae. The small size of the LDC genome and its unrelatedness to those of M. leprae and organisms of the CMN group shows the uniqueness of LDC.", }