The genomes of and leprosy-derived corynebacteria (LDC), which have a similar base composition of guanine+cytosine 56 mol%, have been compared with those of reference bacteria of the CMN group (genera ). Genome sizes of three LDC strains were (1.2-2.5) x 10 base pairs. DNA from four of seven LDC strains examined had homology levels >60%. Two other strains had a homology of 40% when compared with the CMN strains and one strain was distinctly different. The DNA from all seven LDC strains gave 0.3-18% hybridisation with that of , 5-16% with reference corynebacteria, 5-12% with , and 2-8% with The small size of the LDC genome and its unrelatedness to those of and organisms of the CMN group shows the uniqueness of LDC.


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