1887

Abstract

Summary

The genomes of and leprosy-derived corynebacteria (LDC), which have a similar base composition of guanine + cytosine 56 mol%, have been compared with those of reference bacteria of the CMN group (genera ). Genome sizes of three LDC strains were (1.2–2.5) × 10 base pairs. DNA from four of seven LDC strains examined had homology levels >60%. Two other strains had a homology of 40% when compared with the CMN strains and one strain was distinctly different. The DNA from all seven LDC strains gave 0.3–18% hybridisation with that of , 5–16% with reference corynebacteria, 5–12% with , and 2–8% with . The small size of the LDC genome and its unrelatedness to those of and organisms of the CMN group shows the uniqueness of LDC.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-27-1-45
1988-09-01
2024-12-12
Loading full text...

Full text loading...

/deliver/fulltext/jmm/27/1/medmicro-27-1-45.html?itemId=/content/journal/jmm/10.1099/00222615-27-1-45&mimeType=html&fmt=ahah

References

  1. Abou-Zeid C., Harboe M., Sundsten B., Cocito C. 1985; Crossreactivity of antigens from the cytoplasm and cell walls of some corynebacteria and mycobacteria. Journal of Infectious Diseases 151:170–178
    [Google Scholar]
  2. Athwal R. S., Deo S. S., Imaeda T. 1984; Deoxyribonucleic acid relatedness among Mycobacterium leprae, Mycobacterium lepraemurium and selected bacteria by dot blot and spectrophotometric deoxyribonucleic acid hydridization assays. International Journal of Systematic Bacteriology 34:371–375
    [Google Scholar]
  3. Baess I. 1979; Deoxyribonucleic acid relatedness among species of slowly-growing mycobacteria. Acta Pathologica et Micro-biologica Scandinavica Section B 87:221–226
    [Google Scholar]
  4. Baess I., Mansa B. 1978; Determination of genome size and base ratio on deoxyribonucleic acid from mycobacteria. Acta Pathologica et Microbiologica Scandinavica Section B 87:309–312
    [Google Scholar]
  5. Baess I., Bentzon M. W. 1978; Deoxyribonucleic acid hybridization between different species of mycobacteria. Acta Pathologica et Microbiologica Scandinavica Section B 86:71–76
    [Google Scholar]
  6. Barksdale L. 1970; Corynebacterium diphtheriae and its relatives. Bacteriological Reviews 34:378–422
    [Google Scholar]
  7. Barksdale L., Kim K. S. 1977; Mycobacterium. Bacteriological Reviews 41:217–372
    [Google Scholar]
  8. Beaman B. L., Kim K. S., Laneelle M. A., Barksdale L. 1974; Chemical characterization of organisms isolated from leprosy patients. Journal of Bacteriology 117:1320–1329
    [Google Scholar]
  9. Britten R. J., Kohne D. E. 1968; Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms. Science 161:529–540
    [Google Scholar]
  10. Brown S., Lanelle M. A., Asselineau J., Barksdale L. 1984; Description of Corynebacterium tuberculostearicum sp. nov., a leprosy-derived corynebacterium. Annales de Microbiologie (Institut Pasteur) 135B:251–267
    [Google Scholar]
  11. Cocito C., Delville J. 1983; Properties of microorganisms from human leprosy lesions. Reviews of Infectious Diseases 5:649–657
    [Google Scholar]
  12. Cocito C., Delville J. 1985; Biological, chemical, immunological and staining properties of bacteria isolated from tissues of leprosy patients. European Journal of Epidemiology 1:202–231
    [Google Scholar]
  13. Coene M., Cocito C. 1985; A microanalytical procedure for determination of the base composition of DNA. European Journal of Biochemistry 150:475–479
    [Google Scholar]
  14. Clark-Curtiss J. E., Jacobs W. R., Dochery M. A., Ritchie L. R., Curtiss R. 1985; Molecular analysisof DNA and construction of genomic libraries of Mycobacterium leprae. Journal of Bacteriology 161:1093–1102
    [Google Scholar]
  15. Danhaive P., Hoet P., Cocito C. 1982; Base compositions and homologies of deoxyribonucleic acids of corynebacteria isolated from human leprosy lesions and of related microorganisms. International Journal of Systematic Bacteriology 32:70–76
    [Google Scholar]
  16. DeKesel M., Coene M., Portaels F., Cocito C. 1987; Analysis of deoxyribonucleic acid from armadillo-derived mycobacteria. International Journal of Systematic Bacteriology 37:317–322
    [Google Scholar]
  17. Delville J., Pichel A. M. 1975; L’agent etiologique de la lepre est-il invariablement acido-alcoolo resistant au Ziehl-Neelsen? Problemes souleves par les isolements a partir de lesions lepreuses de germes non acido-alcoolo resistants. Acta Leprologica 59/60:83–91
    [Google Scholar]
  18. De Ley J., Cattoir H., Reynaerts A. 1970; The quantitative measurement of DNA hybridization from renaturation rates. European Journal of Biochemistry 12:133–142
    [Google Scholar]
  19. Dove W. F., Davidson N. 1962; Cation effects of the denaturation of DNA. Journal of Molecular Biology 5:467–478
    [Google Scholar]
  20. Draper P. 1976; Cell walls of Mycobacterium leprae. International Journal of Leprosy 44:95–98
    [Google Scholar]
  21. Gailly C., Sandra P., Verzele M., Cocito C. 1982; Analysis of mycolic acids from a group of corynebacteria by capillary gas chromatography and mass spectrometry. European Journal of Biochemistry 125:83–94
    [Google Scholar]
  22. Goodfellow M., Wayne L. G. 1982; Taxonomy and nomenclature. In Ratledge C., Stanford J. (eds) Biology of the mycobacteria Academic Press; London: pp 471–523
    [Google Scholar]
  23. Gueur M. C., Harboe M., Fontaine F., Delville J., Cocito C. 1983; Comparison of the cytoplasmic antigens of leprosy-derived corynebacteria and some mycobacteria. Scandinavian Journal of Immunology 17:497–506
    [Google Scholar]
  24. Hottat F., Coene M., Cocito C. 1987; DNA methylation in leprosy-associated bacteria: Mycobacterium leprae and Corynebacterium tuberculostearicum. Medical Microbiology and Immunology 176:33–45
    [Google Scholar]
  25. Imaeda T., Kirchheimer W. F., Barksdale L. 1982; DNA isolated from Mycobacterium leprae: genome size, base ratio, and homology with other related bacteria as determined by optical DNA-DNA reassociation. Journal of Bacteriology 150:414–417
    [Google Scholar]
  26. Janczura E., Zeid C., Gailly C., Cocito C. 1981a; Chemical identification of some cell-wall components of microorganisms isolated from human leprosy lesions. Zentralblatt fur Bakteriologie I. Abt. Orig. A 251:114–125
    [Google Scholar]
  27. Janczura E., Bouille M., Cocito C., Ghuysen J. M. 1981b; Primary structure of the wall peptidoglycan of leprosy-derived corynebacteria. Journal of Bacteriology 145:775–779
    [Google Scholar]
  28. Johnson J. L. 1985; DNA reassociation and RNA hybridization of bacterial nucleic acids. Methods in Microbiology 18:33–73
    [Google Scholar]
  29. Kirchheimer W. F., Storrs E. E. 1971; Attempts to establish the armadillo (Dasypus novemcinctus, Limm.) as a model for the study of leprosy. I. Report of lepromatoid leprosy in an experimentally infected armadillo. International Journal of Leprosy 39:693–702
    [Google Scholar]
  30. Laub R., Delville J., Cocito C. 1978; Immunological relatedness of ribosomes from mycobacteria, nocardiae and corynebacteria, and microorganisms in leprosy lesions. Infection and Immunity 22:540–547
    [Google Scholar]
  31. McFadden J. J., Butcher P. D., Chiodini R. J., Hermon-Taylor J. 1987; Determination of genome size and DNA homology between an unclassified Mycobacterium species isolated from patients with Crohn’s disease and other mycobacteria. Journal of General Microbiology 133:211–214
    [Google Scholar]
  32. Portaels F., DeRidder K., Pattyn S. R. 1985; Cultivable mycobacteria isolated from organs of armadillos uninoculated and inoculated with Mycobacterium leprae. Annales de Microbiologie (Institut Pasteur) 136A:181–190
    [Google Scholar]
  33. Portaels F. 1986; A cooperative taxonomic study of mycobacteria isolated from armadillos infected with Mycobacterium leprae. Journal of General Microbiology 132:2693–2707
    [Google Scholar]
  34. Ridell M. 1977; Studies on corynebacterial precipitinogens common to mycobacteria, nocardiae and rhodochrous. International Archives of Allergy and Applied Immunology 55:468–475
    [Google Scholar]
/content/journal/jmm/10.1099/00222615-27-1-45
Loading
/content/journal/jmm/10.1099/00222615-27-1-45
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error