Rapid antibiotic susceptibility tests on Enterobacteriaceae by ATP bioluminescence Free

Abstract

Summary

The susceptibility of 76 clinical isolates of Enterobacteriaceae to ampicillin, piperacillin and gentamicin was assessed by ATP bioluminescence in a 4-h test. For most organisms tested ( and ), there was good correlation with traditional MIC values estimated on 18-h cultures. However strains of showed false resistance to the -lactam agents with the ATP method; and concordance was achieved only after manipulation of the growth conditions. Our method is simpler than those described previously, though currently it is still labour-intensive and expensive.

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1988-02-01
2024-03-29
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