1887

Abstract

Summary.

A strain of associated with chronic urinary tract infection was found to produce an EDTA-sensitive IgA protease that cleaved the IgA heavy chain into two fragments at sites different from those attacked by other microbial IgA1 proteases. Another 14 . strains of diverse type and from various clinical conditions also produced a similar IgA protease. This enzyme may be a virulence determinant of . .

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-24-2-175
1987-09-01
2022-01-23
Loading full text...

Full text loading...

/deliver/fulltext/jmm/24/2/medmicro-24-2-175.html?itemId=/content/journal/jmm/10.1099/00222615-24-2-175&mimeType=html&fmt=ahah

References

  1. Adegbola R A, Old D C, Senior B W. 1983; The adhesins and fimbriae of Proteus mirabilis strains associated with high and low affinity for the urinary tract. Journal of Medical Microbiology 16:427–431
    [Google Scholar]
  2. Bergstrom T. 1972; Sex differences in childhood urinary tract infection. Archives of Diseases of Childhood 47:227–232
    [Google Scholar]
  3. Blake M S, Swanson J. 1978; Studies on gonococcus infection. XVI. Purification of Neisseria gonorrhoeae immunoglobulin A1 protease. Infection and Immunity 22:350–358
    [Google Scholar]
  4. Braude A I, Siemienski J. 1960; Role of bacterial urease in experimental pyelonephritis. Journal of Bacteriology 80:171–179
    [Google Scholar]
  5. Braude A I, Siemienski J, Shapiro A B. 1960; The role of bacterial urease in the pathogenesis of pyelonephritis. Quinn E L, Kass E H. Biology of pyelonephritis Churchill Livingstone; London:69–88
    [Google Scholar]
  6. Fairley K F. 1971; Site of infection in acute urinary tract infection in general practice. Lancet 2:615–618
    [Google Scholar]
  7. Griffith D P, Musher D M, Campbell J W. 1973; Inhibition of bacterial urease. Investigative Urology 11:234–238
    [Google Scholar]
  8. Hallett R J, Pead L, Maskell R. 1976; Urinary infection in boys. A three year prospective study. Lancet 2:1107–1110
    [Google Scholar]
  9. Hunter W M, Greenwood F C. 1962; Preparation of iodine-131 labelled human growth hormone of high specific activity. Nature 194:495–496
    [Google Scholar]
  10. Khan A J, Ubriani R S, Bombach E, Agbayani M M, Ratner H, Evans H E. 1978; Initial urinary tract infection caused by Proteus mirabilis in infancy and childhood. Journal of Pediatrics 93:791–793
    [Google Scholar]
  11. Kilian M, Mestecky J, Schrohenloher R E. 1979; Pathogenic species of the genus Haemophilus and Streptococcus pneumoniae produce immunoglobulin A1 protease. Infection and Immunity 26:143–149
    [Google Scholar]
  12. Kilian M, Thomsen B, Petersen T E, Bleeg H S. 1983a; Occurrence and nature of bacterial IgA proteases. Annals of the New York Academy of Sciences 409:612–624
    [Google Scholar]
  13. Kilian M, Thomsen B, Petersen T E, Bleeg H. 1983b; Molecular biology of Haemophilus influenzae IgA1 proteases. Molecular Immunology 20:1051–1058
    [Google Scholar]
  14. Laemmli U K. 1970; Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680–685
    [Google Scholar]
  15. Larsson P, Olling S. 1977; O antigen distribution and sensitivity to the bactericidal effect of normal human serum of Proteus strains from clinical specimens. Medical Microbiology and Immunology 163:77–82
    [Google Scholar]
  16. MacLaren D M. 1968; The significance of urease in Proteus pyelonephritis : a bacteriological study. Journal of Pathology and Bacteriology 96:45–56
    [Google Scholar]
  17. MacLaren D M. 1969; The significance of urease in Proteus pyelonephritis : a histological and biochemical study. Journal of Pathology 97:43–49
    [Google Scholar]
  18. Male C J. 1979; Immunoglobulin A1 protease production by Haemophilus influenzae and Streptococcus pneumoniae . Infection and Immunity 26:254–261
    [Google Scholar]
  19. Mulks M H, Plaut A G. 1978; IgA protease production as a characteristic distinguishing pathogenic from harmless Neisseriaceae . New England Journal of Medicine 299:973–976
    [Google Scholar]
  20. Mulks M H, Kornfeld S J, Plaut A G. 1980a; Specific proteolysis of human IgA by Streptococcus pneumoniae and Haemophilus influenzae . Journal of Infectious Diseases 141:450–456
    [Google Scholar]
  21. Mulks M H, Plaut A G, Feldman H A, Frangione B. 1980b; IgA proteases of two distinct specificities are released by Neisseria meningitidis . Journal of Experimental Medicine 152:1442–1447
    [Google Scholar]
  22. Musher D M, Griffith D P, Yawn D, Rossen R D. 1975; Role of urease in pyelonephritis resulting from urinary tract infection with Proteus . Journal of Infectious Diseases 131:177–181
    [Google Scholar]
  23. Pazin G J, Braude A I. 1974; Immobilizing antibodies in urine. II. Prevention of ascending spread of Proteus mirabilis . Investigative Urology 12:129–133
    [Google Scholar]
  24. Peerbooms P G H, Verweij A M J J, MacLaren D M. 1983; Investigation of the haemolytic activity of Proteus mirabilis strains. Antonie van Leeuwenhoek 49:1–11
    [Google Scholar]
  25. Peerbooms P G H, Verweij A M J J, MacLaren D M. 1984; Vero cell invasiveness of Proteus mirabilis . Infection and Immunity 43:1068–1071
    [Google Scholar]
  26. Plaut A G, Gilbert J V, Artenstein M S, Capra J D. 1975; Neisseria gonorrhoeae and Neisseria meningitidis : extracellular enzyme cleaves human immunoglobulin A. Science 190:1103–1105
    [Google Scholar]
  27. Senior B W. 1977; Typing of Proteus strains by proticine production and sensitivity. Journal of Medical Microbiology 10:7–17
    [Google Scholar]
  28. Senior B W. 1979; The special affinity of particular types of Proteus mirabilis for the urinary tract. Journal of Medical Microbiology 12:1–8
    [Google Scholar]
  29. Senior B W. 1983a; Proteus morgani is less frequently associated with urinary tract infections than Proteus mirabilis—an explanation. Journal of Medical Microbiology 16:317–322
    [Google Scholar]
  30. Senior B W. 1983b; The purification, structure and synthesis of proticine 3. Journal of Medical Microbiology 16:323–331
    [Google Scholar]
  31. Senior B W, Bradford N C, Simpson D S. 1980; The ureases of Proteus strains in relation to virulence for the urinary tract. Journal of Medical Microbiology 13:507–512
    [Google Scholar]
  32. Senior B W, Larsson P. 1983; A highly discriminatory multityping scheme for Proteus mirabilis and Proteus vulgaris . Journal of Medical Microbiology 16:193–202
    [Google Scholar]
  33. Senior B W, Leslie D L. 1986; Rare occurrence of Proteus vulgaris in faeces: a reason for its rare association with urinary tract infections. Journal of Medical Microbiology 21:139–144
    [Google Scholar]
  34. Silverblatt F J. 1974; Host-parasite interaction in the rat renal pelvis. A possible role for pili in the pathogenesis of pyelonephritis. Journal of Experimental Medicine 140:1696–1711
    [Google Scholar]
  35. Silverblatt F J, Ofek I. 1978; Influence of pili on the virulence of Proteus mirabilis in experimental hematogenous pyelonephritis. Journal of Infectious Diseases 138:664–667
    [Google Scholar]
  36. Sorensen C H, Kilian M. 1984; Bacterium-induced cleavage of IgA in nasopharyngeal secretions from atopic children. Acta Pathologica, Microbiologica et Immunologica Scandinavica Section C 92:85–87
    [Google Scholar]
  37. Svandborg Edén C, Larsson P, Lomberg H. 1980; Attachment of Proteus mirabilis to human urinary sediment epithelial cells in vitro is different from that of Escherichia coli . Infection and Immunity 27:804–807
    [Google Scholar]
  38. Umezawa H, Aoyagi T. 1977; Activities of proteinase inhibitors of microbial origin. Barrett A J. Proteinases in mammalian cells and tissues North Holland, Amsterdam:637–662
    [Google Scholar]
  39. Walkey F A, Judge T G, Thompson J, Sarkari N B. 1967; Incidence of urinary infection in the elderly. Scottish Medical Journal 12:411–414
    [Google Scholar]
  40. Young H. 1978; Identification and penicillinase testing of Neisseria gonorrhoeae from primary isolation cultures on modified New York City medium. Journal of Clinical Microbiology 7:247–250
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-24-2-175
Loading
/content/journal/jmm/10.1099/00222615-24-2-175
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error