1887

Abstract

Summary.

Using an in-vitro adherence assay it was observed that the number of cells that attached to individual buccal mucosal cells varied greatly. Three mucosal-cell characteristics—state of aggregation, size and viability—that might influence yeast adhesion were studied. The number of attached yeast cells per mucosal cell varied from 0 to 32. The majority of buccal cells (88%) had none or very few yeasts attached, whereas a minority of cells (12%) bound more than one half of all the attached yeasts. In donors whose buccal cells had large numbers of attached yeasts this percentage increased and the number of cells with no attached yeast cells fell. Cells of an intermediate size (36–70m) had a greater affinity for yeasts than did cells of other sizes. Buccal cell viability appeared not to be necessary for adhesion of yeasts. No significant differences were observed in the number of yeast cells attached to single buccal cells compared with attachment to buccal cells within sheets. It would appear, therefore, that there are distinct subpopulations of epithelial cells with high and low affinity for attachment by . Mucosal cell size or viability might influence this affinity.

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1987-09-01
2022-10-02
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References

  1. Bartelt M A, Duncan J L. 1978; Adherence of group A streptococci to human epithelial cells. Infection and Immunity 20:200–208
    [Google Scholar]
  2. Botta G A. 1981; Possible role of hormones in the observed changes in adhesion of several microorganisms to epithelial cells from different body sites. FEMS Microbiology Letters 11:69–72
    [Google Scholar]
  3. Fowler J E, Stamey T A. 1977; Studies of the introital colonization in women with recurrent urinary infections. VIII. The role of bacterial adherence. Journal of Urology 117:472–476
    [Google Scholar]
  4. Gibbons R J, Van Houte J. 1975; Bacterial adherence in oral microbial ecology. Annual Review of Microbiology 29:19–44
    [Google Scholar]
  5. Kennedy M J, Volz P A. 1985; Ecology of Candida albicans gut colonization : inhibition of Candida adhesion, colonization and dissemination from the gastrointestinal tract by bacterial antagonism. Infection and Immunity 49:654–663
    [Google Scholar]
  6. Kimura L H, Pearsall N N. 1980; Relationship between germination of Candida albicans and increased adherence to human buccal epithelial cells. Infection and Immunity 28:464–468
    [Google Scholar]
  7. King R D, Lee J C, Morris A L. 1980; Adherence of Candida albicans and other Candida species to mucosal epithelial cells. Infection and Immunity 27:667–674
    [Google Scholar]
  8. Lee J C, King R D. 1983; Characterization of Candida albicans adherence to human vaginal epithelial cells in vitro. Infection and Immunity 41:1024–1030
    [Google Scholar]
  9. Odds F C. 1979 Candida and candidosis Leicester University Press;
    [Google Scholar]
  10. Rippon J W. 1982; Candidosis and the pathogenic yeasts. Rippon J W. Medical mycology. The pathogenic fungi and the pathogenic actinomycetes W B Saunders; Philadelphia, PA:484–531
    [Google Scholar]
  11. Rosenstein I J, Grady D, Hamilton-Miller J M T, Brumfitt W. 1985; Relationship between adhesion of Escherichia coli to uro-epithelial cells and the pathogenesis of urinary infection: problems in methodology and analysis. Journal of Medical Microbiology 20:335–344
    [Google Scholar]
  12. Sandin R L, Rogers A L, Patterson R J, Beneke E S. 1982; Evidence for mannose-mediated adherence of Candida albicans to human buccal cells in vitro. Infection and Immunity 35:79–85
    [Google Scholar]
  13. Segal E, Soroka A, Schechter A. 1984; Correlative relationship between adherence of Candida albicans to human vaginal epithelial cells in vitro and candidal vaginitis. Sabouraudia 22:191–200
    [Google Scholar]
  14. Skerl K G, Calderone R A, Segal E, Sreevalsan T, Scheld W M. 1984; In vitro binding of Candida albicans yeast cells to human fibronectin. Canadian Journal of Microbiology 30:221–227
    [Google Scholar]
  15. Sklavounou A, Germaine G R. 1980; Adherence of oral streptococci to keratinized and nonkeratinized human oral epithelial cells. Infection and Immunity 27:686–689
    [Google Scholar]
  16. Sobel J D, Muller G, Buckley H R. 1984; Critical role of germ tube formation in the pathogenesis of candidal vaginitis. Infection and Immunity 44:576–580
    [Google Scholar]
  17. Sobel J D, Myers P G, Kaye D, Levison M E. 1981; Adherence of Candida albicans to human vaginal and buccal epithelial cells. Journal of Infectious Diseases 143:76–82
    [Google Scholar]
  18. Svanborg Eden C, Eriksson B, Hanson L A. 1977; Adhesion of Escherichia coli to human uroepithelial cells in vitro. Infection and Immunity 18:767–774
    [Google Scholar]
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