1887

Abstract

Summary

Spirochaetes were demonstrated in material from patients with Lyme disease by short-time high-concentrate silver impregnation after treatment with amylase. Removal of mucoid material was essential to visualise . Lyme spirochaetes were demonstrated in material from 23 patients with Lyme disease—erythema chronicum migrans (ECM) 10, lymphadenosis benigna cutis (LABC) 7, arthritis 4 and Bannwarth’s syndrome 2. Spirochaetes were localised in the subepidermal zone, peri- and intravascularly, and in collagen fibres in ECM and LABC, and beneath the synovial lining cells in arthritis, producing marked vascular changes with fibrosis and synovial hyperplasia. Spirochaetes were also demonstrated in CSF from a patient with Bannwarth’s syndrome.

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/content/journal/jmm/10.1099/00222615-23-3-261
1987-05-01
2022-01-27
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References

  1. Berger B. W., Clemmensen O. J., Ackerman A. B. 1983; Lyme disease is a spirochetosis. A review of the disease and evidence for its cause. American Journal ofDermatopathology 5:111–124
    [Google Scholar]
  2. Bosma R. B. 1984; Spirochetenkleuring volgens “Gabriel Steiner”. Histotechniek 5:162–166
    [Google Scholar]
  3. Bridges C. H., Luna L. 1957; Kerr’s improved Warthin-Starry technic. Study of the permissible variations. Laboratory Investigation 6:357–367
    [Google Scholar]
  4. Johnston Y. E. 1985; Lyme arthritis spirochetes found in synovial microangiopathic lesions. American Journal of Pathology 118:26–34
    [Google Scholar]
  5. Komblatt A. N., Steere A. C., Brownstein D. G. 1984; Experimental Lyme disease in rabbits: spirochetes found in erythema migrans and blood. Infection and Immunity 46:220–23
    [Google Scholar]
  6. Steere A. C. 1984; The spirochetal etiology of Lyme disease. New England Journal of Medicine 308:733–740
    [Google Scholar]
  7. Steiner G. 1950; Modified silver stain of microorganisms in tissues. American Journal of Clinical Pathology 20:489–490
    [Google Scholar]
  8. Wilske B., Schierz G., Mursic V., Weber K., Pfister H. W., Einhaupl K. 1984; Serological diagnosis of erythema migrans disease and related disorders. Infection 12:331–337
    [Google Scholar]
  9. Wos S. M., Wicher K. 1985; Antigenic evidence for host origin of exudative fluids in lesions of Treponema pallidum-infected rabbits. Infection and Immunity 47:228–233
    [Google Scholar]
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