%0 Journal Article %A Tennent, Jan M. %A May, J. W. %A Skurray, R. A. %T Characterisation of Chloramphenicol Resistance Plasmids of Staphylococcus Aureus and S. Epidermidis by Restriction Enzyme Mapping Techniques %D 1986 %J Journal of Medical Microbiology, %V 22 %N 1 %P 79-84 %@ 1473-5644 %R https://doi.org/10.1099/00222615-22-1-79 %I Microbiology Society, %X Summary Chloramphenicol resistance (Cmr) plasmids pSK2 and pSK5 from Staphylococcus aureus and pSK 102 and pSK 103 from S. epidermidis have been characterised and detailed restriction endonuclease cleavage maps constructed. TaqI digestion profiles illustrated the identity of pSK 5 and pSK 102 and also revealed a high degree of similarity between these four Cmr plasmids from Australian staphylococci and three Cmr plasmids from S. aureus strains of geographically unrelated origin. DNA-DNA hybridisation indicated that the chloramphenicol acetyltransferase determinant carried by pSK 5/pSK 102 could be found on other structurally-distinct Cmr plasmids. The role of S. epidermidis as a reservoir for Cmr plasmids found in S. aureus is discussed. %U https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-22-1-79