1887

Abstract

Summary

Chloramphenicol resistance (Cm) plasmids pSK2 and pSK5 from and pSK 102 and pSK 103 from have been characterised and detailed restriction endonuclease cleavage maps constructed. I digestion profiles illustrated the identity of pSK 5 and pSK 102 and also revealed a high degree of similarity between these four Cm plasmids from Australian staphylococci and three Cm plasmids from strains of geographically unrelated origin. DNA-DNA hybridisation indicated that the chloramphenicol acetyltransferase determinant carried by pSK 5/pSK 102 could be found on other structurally-distinct Cm plasmids. The role of as a reservoir for Cm plasmids found in is discussed.

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1986-08-01
2022-01-27
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