1887

Abstract

Summary

Interactions between trophozoites of and peritoneal exudate macrophages from unsensitised and antigen-sensitised animals were studied Normal macrophages killed trophozoites to some extent. This killing capacity was enhanced by prior sensitisation of the animals with specific antigen. Incorporation of anti-amoebic antiserum in the amoeba-macrophage mixture greatly enhanced the killing capacity of macrophages. Fraction one (F-I) of a crude amoebic extract was most effective in enhancing the cytotoxicity of macrophages by prior sensitisation and anti-F-I serum was the most effective antiserum. The cytotoxicity-inducing capacity of the immune serum resided in the IgG but not in the IgM fraction.

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/content/journal/jmm/10.1099/00222615-22-1-17
1986-08-01
2019-12-11
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-22-1-17
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