1887

Abstract

SUMMARY:

Rabbit serum hyperimmune to var serovar , reference strain RGA was conjugated to the chemiluminescent label ABEI (6-[N-(4-aminobutyl)-N-ethyl amino]-2,3-dihydro-phthalazine-1,4-dione) in the presence of the coupling agent, EDC (1-ethyl-3(3-dimethyl amino-propyl)-carbodiimide HCl). The luminescent conjugate was incubated with homologous and heterologous antigens. The results indicate that chemiluminescence may provide an accurate and rapid method of detecting leptospires in biological fluids.

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/content/journal/jmm/10.1099/00222615-21-4-353
1986-06-01
2019-10-13
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