1887

Abstract

Summary

Two hundred and eighty-seven coliform bacteria were isolated from 116 rectal swabs or faecal specimens obtained from 113 patients. By means of plasmid analysis and resistance transfer (R-transfer) was found to differ from other enteric genera in plasmid distribution. Criteria were proposed that enabled in-vivo "R-transfer potential" and in-vivo "R-transfer rate" to be calculated. From each of 22 of the 113 patients numerous coliforms were isolated, of which at least one per patient contained one or more self-transmissible R-plasmids potentially transferable to 43 other coliforms. Evidence indicated that R-plasmid transfer had occurred on two of the 43 potential occasions. These results are discussed in the context of plasmid ecology in the human host.

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1986-06-01
2024-04-20
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