1887

Abstract

Summary

The role of in the pathogenesis of acute appendicitis was studied in 135 patients in four patient groups: normal (17); phlegmonous appendicitis (17); gangrenous appendicitis (75); and septic complications of appendicitis (26). Aerobic and anaerobic bacteria were isolated from all groups and members of the ‘ group’ were the most common anaerobic isolates. The rate of isolation of was similar from normal and inflamed appendices but was significantly higher from those with septic complications (p<0-01). Antibodies against were demonstrated in patients of all groups and occurred with similar frequencies in patients with normal and inflamed appendices but at a significantly higher rate in those with septic complications (p<0 01). Whereas patients in this latter group showed IgM- antibody responses to only, those with acute appendicitis had IgM antibodies against a wide range of organisms of the group’ which suggests that does not play a significant role in acute appendicitis but may be a major cause of its septic complications.

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1986-05-01
2022-01-22
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