RT Journal Article SR Electronic(1) A1 Tavendale, Anne A1 Old, D. C.YR 1985 T1 Haemagglutinins and Adhesion of Escherichia Coli To Hep2 Epithelial Cells JF Journal of Medical Microbiology, VO 20 IS 3 SP 345 OP 353 DO https://doi.org/10.1099/00222615-20-3-345 PB Microbiology Society, SN 1473-5644, AB Summary Strains of Escherichia coli producing type-1 fimbriae, associated with mannose-sensitive haemagglutinin (MSHA), or three antigenically different kinds of ‘MRE’ fimbriae, associated with mannose-resistant and eluting haemagglutinins (MREHAs), adhered poorly to HEp2 epithelial cells in an in-vitro adhesion model previously used to demonstrate the importance of motility and type-1 fimbriae for the attachment of strains of Salmonella typhimurium to HEp2 cells. Strains of E. coli producing narrow-spectrum MREHA, agglutinating human erythrocytes only of 14 red-cell species tested, adhered well to HEp2 cells, particularly so when bacteria produced MSHA (and type-1 fimbriae) along with the narrow-spectrum ‘man-only’ MREHA. These findings are discussed with regard to recent observations suggesting that narrow-spectrum ‘man-only’ MREHA in E. coli may be associated with fine, fibrillar appendages 2-nm wide., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-20-3-345