@article{mbs:/content/journal/jmm/10.1099/00222615-20-3-345, author = "Tavendale, Anne and Old, D. C.", title = "Haemagglutinins and Adhesion of Escherichia Coli To Hep2 Epithelial Cells", journal= "Journal of Medical Microbiology", year = "1985", volume = "20", number = "3", pages = "345-353", doi = "https://doi.org/10.1099/00222615-20-3-345", url = "https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-20-3-345", publisher = "Microbiology Society", issn = "1473-5644", type = "Journal Article", abstract = "Summary Strains of Escherichia coli producing type-1 fimbriae, associated with mannose-sensitive haemagglutinin (MSHA), or three antigenically different kinds of ‘MRE’ fimbriae, associated with mannose-resistant and eluting haemagglutinins (MREHAs), adhered poorly to HEp2 epithelial cells in an in-vitro adhesion model previously used to demonstrate the importance of motility and type-1 fimbriae for the attachment of strains of Salmonella typhimurium to HEp2 cells. Strains of E. coli producing narrow-spectrum MREHA, agglutinating human erythrocytes only of 14 red-cell species tested, adhered well to HEp2 cells, particularly so when bacteria produced MSHA (and type-1 fimbriae) along with the narrow-spectrum ‘man-only’ MREHA. These findings are discussed with regard to recent observations suggesting that narrow-spectrum ‘man-only’ MREHA in E. coli may be associated with fine, fibrillar appendages 2-nm wide.", }