The results of in-vitro sensitivity tests of strains of and type 1 to ampicillin, cephaloridine, chloramphenicol, erythromycin, kanamycin, lincomycin, methicillin, streptomycin, tetracycline, sodium aurothiomalate and tylosin tartrate are reported. They confirm that and are sensitive to tetracycline and chloramphenicol, but show that a number of strains of and type 1 are resistant to these drugs. Some of these strains were also resistant to kanamycin, but most were sensitive to tylosin tartrate.

All the mycoplasmas were resistant to ampicillin and methicillin, and to cephaloridine at concentrations of 25–100 μg per ml. Strains of were sensitive to erythromycin, but most of the other strains were resistant. The mycoplasmas were very variable in their sensitivity to sodium aurothiomalate.

It is suggested that tylosin tartrate is the agent most likely to prove useful for eradicating mycoplasmas from contaminated tissue cultures.


Article metrics loading...

Loading full text...

Full text loading...


Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error