1887

Abstract

Summary

The exposure of cultures of to linoleic acid selected variants that were resistant to aminoglucoside antibiotics. Variants with identical characters were isolated by exposure to an aminoglucoside antibiotic, paromomycin.

The variants grew on nutrient agar as small, intensely pigmented colonies, but tended to revert to the original colonial form. The revertants were sensitive to aminoglucoside antibiotics.

Some of the variants were stimulated to normal growth only by fructose, and others by fructose, acetate, pyruvate, oxaloacetate and aspartate. The latter variants exhibited satellitism around colonies of certain Gram-positive cocci.

Dwarf-colony variants persisted better than the parent staphylococci on normal skin. Their occurrence might be relevant to the survival of staphylococci on carriage sites, particularly in patients being treated with aminoglucoside antibiotics.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-2-3-187
1969-08-01
2020-01-29
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-2-3-187
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error