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The action of the antiseptic chlorhexidine has been tested against 205 strains of the genus Proteus. No strain was found to survive, under the conditions of the test, a concentration of 1 in 5000. The four species of the genus, however, varied in sensitivity. In general, Pr. mirabilis was the most resistant; Pr. rettgeri and Pr. morganii were the most sensitive; Pr. vulgaris tended to be less resistant than Pr. mirabilis and more so than Pr. rettgeri and Pr. morganii.
The same strains were also tested against a number of chemotherapeutic drugs. Evidence that resistance to chlorhexidine among Pr. mirabilis strains was associated with multiple drug-resistance could not be established.