1887

Abstract

SUMMARY

The susceptibility of chicks to enteritis caused by was studied. Three-day-old chicks did not develop enteritis after oral infection but chicks infected within 12 h of hatching developed gastroenteritis. The incubation period correlated with the inoculum size. Initially, infected chicks developed blood- and mucus-containing stools, although watery diarrhoea often occurred late in the course of the disease. Recurrences of the enteric manifestations were common but only two out of 170 infected chicks died. was recovered from sites throughout the intestine; the highest concentrations were present in the caecum and large intestine. Both the upper and lower gastrointestinal tract were affected and cellular infiltration of the gastric mucosa and the intestinal lamina propria was observed. Organisms resembling were seen within the intestinal epithelium and lamina propria by electronmicroscopy. The newly hatched chick provides a reproducible and sensitive model of Campylobacter enteritis.

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1984-10-01
2022-01-17
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References

  1. Abrams G. D., Bishop J. E. 1966; Effect of the normal microbial flora on the resistance of the small intestine to infection. Journal of Bacteriology 92:1604–1608
    [Google Scholar]
  2. Anders B. J., Lauer B. A., Paisley J. W. 1981; Campylobacter gastroenteritis in neonates. American Journal of Diseases in Children 135:900–902
    [Google Scholar]
  3. Berg R. D., Garlington A. W. 1979; Translocation of certain indigenous bacteria from the gastrointestinal tract to the mesenteric lymph nodes and other organs in a gnotobiotic mouse model. Infection and Immunity 23:403–411
    [Google Scholar]
  4. Blaser M. J., Duncan D. J., Warren G. H., Wang W.-L. L. 1983; Experimental Campylobacter jejuni infection of adult mice. Infection and Immunity 39:908–916
    [Google Scholar]
  5. Blaser M. J., Hardesty H. L., Powers B., Wang W.-L. L. 1980; Survival of Campylobacter fetus subsp. jejuni in biological milieus. Journal of Clinical Microbiology 11:309–313
    [Google Scholar]
  6. Butzler J. P., Skirrow M. B. 1979; Campylobacter enteritis. Clinics in Gastroenterology 8:737–765
    [Google Scholar]
  7. Caldwell M. B., Walker R. I., Stewart S. D., Rogers J. E. 1983; A simple adult rabbit model for Campylobacter jejuni enteritis. Infection and Immunity 42:1176–1182
    [Google Scholar]
  8. Colgan T., Lambert J. R., Newman A., Luk S. C. 1980; Campylobacter jejuni enterocolitis. A clinicopathologic study. Archives in Pathology and Laboratory Medicine 104:571–574
    [Google Scholar]
  9. Dawes C. J. 1971; Biological techniques in electron microscopy. Barnes and Noble; New York:
    [Google Scholar]
  10. Field L. H., Underwood J. L., Pope L. M., Berry L. J. 1981; Intestinal colonization of neonatal animals by Campylobacter fetus subsp. jejuni . Infection and Immunity 33:884–892
    [Google Scholar]
  11. Fitzgeorge R. B., Baskerville A., Lander K. P. 1981; Experimental infection of rhesus monkeys with a human strain of Campylobacter jejuni . Journal of Hygiene 86:343–351
    [Google Scholar]
  12. Fuller R., Jayne-Williams D. J. 1970; Resistance of the fowl (Gallus domesticus) to invasion by its intestinal flora. II. Clearance of translocated intestinal bacteria. Research in Veterinary Sciences 11:368–374
    [Google Scholar]
  13. George H. A., Hoffman P. S., Smibert R. M., Krieg N. R. 1978; Improved media for growth and aerotolerance of Campylobacter fetus . Journal of Clinical Microbiology 8:36–41
    [Google Scholar]
  14. Karmali M. A., Fleming P. C. 1979; Campylobacter enteritis in children. Journal of Pediatrics 94:527–533
    [Google Scholar]
  15. Kawamura A. 1977; Fluorescent antibody techniques and their applications. 2nd edn University Park Press; Baltimore:
    [Google Scholar]
  16. Kent T. H., Formal S. B., Labrec E. H. 1966; Salmonella gastroenteritis in rhesus monkeys. Archives in Pathology 82:272–279
    [Google Scholar]
  17. Kent T. H., Formal S. B., Labrec E. H., Sprinz H., Maenza R. M. 1967; Gastric shigellosis in rhesus monkeys. American Journal of Pathology 51:259–267
    [Google Scholar]
  18. Lawrence E. C., Arnaud-Battandier F., Grayson J., Koski IR, Dooley N. J., Muchmore A. V., Blaese R. M. 1981; Ontogeny of humoral immune function in normal chickens: a comparison of immunoglobulin-secreting cells in bone marrow, spleen, lungs, and intestine. Clinical and Experimental Immunology 43:450–457
    [Google Scholar]
  19. Lior H., Woodward D. L., Edgar J. A., Laroche L. J., Gill P. 1982; Serotyping of Campylobacter jejuni by slide agglutination based on heat-labile antigenic factors. Journal of Clinical Micro biology 15:761–768
    [Google Scholar]
  20. Luna L. G. 1968; Manual of histologic staining methods of the Armed Forces Institute of Pathology. 3rd edn McGraw-Hill Book Co.; New York:
    [Google Scholar]
  21. Madge D. S. 1980; Campylobacter enteritis in young mice. Digestion 20:389–394
    [Google Scholar]
  22. Manninen K. I., Prescott J. F., Dohoo I. R. 1982; Pathogenicity of Campylobacter jejuni isolates from animals and humans. Infection and Immunity 38:46–52
    [Google Scholar]
  23. Michalak D. M., Perrault J., Gilchrist M. J., Dozois R. R., Carney J. A., Sheedy P. F. 1980; Campylobacter fetus ss. jejuni: a cause of massive lower gastrointestinal hemorrhage. Gastroenterology 79:742–745
    [Google Scholar]
  24. Miles A. A., Misra S., Irwin J. O. 1938; The estimation of the bacteriocidal power of the blood. Journal of Hygiene 38:732–749
    [Google Scholar]
  25. National Research Council. Institute of Laboratory Animal Resources 1966; Standards and guidelines for the breeding, care, and management of laboratory animals—chickens. Publication no. 1464 Washington, D.C:
    [Google Scholar]
  26. Peckman M. C. 1972; Avian vibrio infections. In Hofstad M. (ed)Diseases of poultry 6th edn Iowa State University Press; Ames, Iowa: pp 332–347
    [Google Scholar]
  27. Prescott J. F., Manninen K. I., Barker I. K. 1982; Experimental pathogenesis of Campylobacter jejuni enteritis—studies in gnotobiotic dogs, pigs, and chickens. In Newell D. G. (ed) Campylobacter—epidemiology, pathogenesis, and biochemistry, MTP Press; Lancaster: pp 170–171
    [Google Scholar]
  28. Prescott J. F., Munroe D. L. 1982; Campylobacter jejuni enteritis in man and domestic animals. Journal of the American Veterinary Medicine Association 181:1524–1530
    [Google Scholar]
  29. Ruiz-Palacios G. M., Escamilla E., Torres N. 1981; Experimental Campylobacter diarrhea in chickens. Infection and Immunity 34:250–255
    [Google Scholar]
  30. Shaffer M. F., Bridges J. F., Clemmer D. I., Pontopidan K. C. 1964; Susceptiblity of chicks to experimental infection with Salmonella typhosa . American Journal of Hygiene 80:377–387
    [Google Scholar]
  31. Shanker S., Rosenfield J. A., Davey G. R., Sorrell T. C. 1982; Campylobacter jejuni: incidence in processed broilers and biotype distribution in human and broiler isolates. Applied and Environmental Microbiology 43:1219–1220
    [Google Scholar]
  32. Skirrow M. B., Benjamin J. 1980a; ‘1001’ Campylobacters: cultural characteristics of intestinal Campylobacters from man and animals. Journal of Hygiene 85:427–442
    [Google Scholar]
  33. Skirrow M. B., Benjamin J. 1980b; Differentiation of enteropathogenic Campylobacter. Journal of Clinical Pathology 33:1122
    [Google Scholar]
  34. Soerjadi A. S., Snoeyenbos G. H., Weinack O. M. 1982; Intestinal colonization and competitive exclusion of Campylobacter fetus subsp. jejuni in young chicks. Avian Diseases 26:520–524
    [Google Scholar]
  35. Takeuchi A. 1967; Electron microscope studies of experimental salmonella infection. I. Penetration into the intestinal epithelium by Salmonella typhimurium . American Journal of Pathology 50:109–136
    [Google Scholar]
  36. Taylor D. J. 1982; Natural and experimental enteric infections with catalase–positive Campylobacters in cattle and pigs. In Newell D. G. (ed) Campylobacter—epidemiology, pathogenesis, and biochemistry, MTP Press; Lancaster: pp 163–167
    [Google Scholar]
  37. Turnbull P. C. B., Richmond J. E. 1978; A model of salmonella enteritis: the behavior of Salmonella enteritidis in chick intestine studied by light and electron microscopy. British Journal of Experimental Pathology 59:64–75
    [Google Scholar]
  38. Welkos S. L. 1982a; A modified broth-disk antibiotic susceptibility test for Campylobacter jejuni . European Journal of Clinical Microbiology 1:354–360
    [Google Scholar]
  39. Welkos S. L. 1982b; Pathogenesis of Campylobacter enteritis—animal model. In Newall D. G. (ed) Campylobacter—epidemiology, pathogenesis, and biochemistry, MTP Press; Lancaster: pp 182
    [Google Scholar]
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