1887

Abstract

SUMMARY

Samples from the posterior vaginal fornix of 102 women with various clinical conditions were analysed by a quantitative method. Aerobes were isolated from all but one of the specimens at a mean concentration of 7.2 log cfu/g and anaerobes from 92 specimens at a mean concentration of 8.1 log cfu/g. In most clinical conditions and in a control group of asymptomatic women, anaerobes outnumbered aerobes by about ten to one (one log unit). The most common organisms were aerobic and anaerobic lactobacilli, coryneforms, spp. and anaerobic gram-positive cocci. Lactobacilli did not appear to confer any protective effect by excluding the presence of other organisms such as or anaerobes. The isolation of anaerobic organisms from the vagina cannot be regarded as being of pathogenic significance without other supporting evidence.

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1984-10-01
2022-01-27
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References

  1. Aly R., Britz M. B., Maibach H. L. 1979; Quantitative microbiology of human vulva. British Journal of Dermatology 101:445–448
    [Google Scholar]
  2. Balsdon M. J., Taylor G. E., Pead L., Masked R. 1980; Corynebacterium vaginale and vaginitis: a controlled trial of treatment. Lancet 1:501–504
    [Google Scholar]
  3. Bartlett J. G., Onderdonk A. B., Drude E., Goldstein C., Anderka M., Alpert S., McCormack W. M. 1977; Quantitative bacteriology of the vaginal flora. Journal of Infectious Diseases 136:271–277
    [Google Scholar]
  4. Bartlett J. G., Moon N. E., Goldstein P. R., Goren B., Onderdonk A. B., Polk B. F. 1978; Cervical and vaginal bacterial flora: Ecologic niches in the female lower genital tract. American Journal of Obstetrics and Gynecology 130:658–661
    [Google Scholar]
  5. Bramley H. M., Dixon R. A., Jones B. M. 1981; Haemophilus vaginalis (Corynebacterium vaginale, Gardnerella vaginalis) in a family planning clinic population. British Journal of Venereal Diseases 57:62–66
    [Google Scholar]
  6. Brown W. J. 1982; Variations in the vaginal bacterial flora: a preliminary report. Annals of Internal Medicine 96:931–934
    [Google Scholar]
  7. Burdon K. L. 1928; Bacterium melaninogenicum from normal and pathologic tissues. Journal of Infectious Diseases 42:161–171
    [Google Scholar]
  8. Clarke T. J. 1977; Methods for studying gut microbes. In Clarke R. T. J., Bauchop T. (eds) The microbial ecology of the gut, Academic Press; London: pp 1–33
    [Google Scholar]
  9. Collins M. D., Jones D. 1981; Distribution of isoprenoid quinone structural types in bacteria and their taxonomic implications. Microbiological Reviews 45:316–354
    [Google Scholar]
  10. Cowan S. T. 1974; Cowan and Steele’s Manual for the identification of medical bacteria. 2nd ed Cambridge University Press; Cambridge:
    [Google Scholar]
  11. Curtis A. H. 1913; A mobile curved anaerobic bacillus in uterine discharges. Journal of Infectious Diseases 12:165–169
    [Google Scholar]
  12. Fagnant J. E., Sanders C. C., Sanders W. E. 1982; Development and evaluation of a biochemical scheme for identification of endocervical lactobacilli. Journal of Clinical Microbiology 16:926–934
    [Google Scholar]
  13. Galask R. P., Larsen B., Ohm M. J. 1976; Vaginal flora and its role in disease entities. Clinical Obstetrics and Gynaecology 19:61–81
    [Google Scholar]
  14. Goldacre M. J., Watt B., Loudon N., Milne L. J. R., Loudon J. D. O., Vessey M. P. 1979; Vaginal microbial flora in normal young women. British Medical Journal 1:1450–1453
    [Google Scholar]
  15. Gorbach S. L., Menda K. B., Thadepalli H., Keith L. 1973; Anaerobic microflora of the cervix of healthy women. American Journal of Obstetrics and Gynecology 117:1053–1055
    [Google Scholar]
  16. Hafiz S., McEntegart M. G., Morton R. S., Waitkins S. A. 1975; Clostridium difficile in the urogenital tract of males and females. Lancet 1:420–421
    [Google Scholar]
  17. Harris J. W., Brown J. H. 1929; A clinical and bacteriological study of 113 cases of streptococcic puerperal infection. Bulletin of the Johns Hopkins Hospital 44:1–31
    [Google Scholar]
  18. Hill G. B. 1980; Anaerobic flora of the female genital tract. In Lambe D. W., Genco R. J., Mayberry Carson K. J. (eds) Anaerobic bacteria, selected topics. Plenum Press; New York: pp 39–50
    [Google Scholar]
  19. Holdeman L. V., Cato E. P., Moore W. E. C. 1977; Anaerobe Laboratory Manual. 4th edn Virginia Polytechnic Institute and State University; Blacksburg, Virginia:
    [Google Scholar]
  20. Hungate R. E. 1950; The anaerobic mesophilic cellulolytic bacteria. Bacteriological Reviews 14:1–49
    [Google Scholar]
  21. Larsen B., Galask R. P. 1982; Vaginal microbial flora: composition and influence of host physiology. Annals of Internal Medicine 96:926–930
    [Google Scholar]
  22. Levison M. E., Corman L. C., Carrington E. R., Kay C. D. 1977; Quantitative microflora of the vagina. American Journal of Obstetrics and Gynecology 127:80–85
    [Google Scholar]
  23. Levison M. E., Trestman I., Quach R., Sladowski C., Flora C. N. 1979; Quantitative bacteriology of the vaginal flora in vaginitis. American Journal of Obstetrics and Gynecology 133:139–144
    [Google Scholar]
  24. Lindner J. G. E. M., Plantema F. H. F., Hoogkamp-Korstanje J. A. A. 1978; Quantitative studies of the vaginal flora of healthy women and of obstetric and gynaecological patients. Journal of Medical Microbiology 11:233–241
    [Google Scholar]
  25. Mays T. D., Holdeman L. V., Moore W. E. C., Rogosa M., Johnson J. L. 1982; Taxonomy of the Genus Veillonella Prevot. International Journal of Systematic Bacteriology 32:28–36
    [Google Scholar]
  26. O’ Farrell S., Wilks M., Nash J. Q., Tabaqchali S. 1984; A selective enrichment broth for the isolation of Clostridium difficile . Journal of Clinical Pathology 37:98–99
    [Google Scholar]
  27. Onderdonk A. B., Polk B. F., Moon N. E., Goren B., Bartlett J. G. 1977; Methods for quantitative vaginal flora studies. American Journal of Obstetrics and Gynecology 128:777–781
    [Google Scholar]
  28. Piot P., van Dyck E., Totten P. A., Holmes K. K. 1982; Identification of Gardnerella (Hemophilus) vaginalis . Journal of Clinical Microbiology 15:19–24
    [Google Scholar]
  29. Riddell R. H., Buck A. C. 1970; Trimethoprim as an additional selective agent in media for the isolation of N. gonorrhoeae . Journal of Clinical Pathology 23:481–483
    [Google Scholar]
  30. Spiegel C. A., Amsel R., Eschenbach D., Schoenknecht F., Holmes K. K. 1980; Anaerobic bacteria in non-specific vaginitis. New England Journal of Medicine 303:601–607
    [Google Scholar]
  31. Sutter V. L., Vargo V. L., Finegold S. M. 1975; Wadsworth anaerobic bacteriology manual. 2nd edn University Extension and School of Medicine UCLA; Los Angeles, CA:
    [Google Scholar]
  32. Tabaqchali S. 1970; The pathophysiological role of small intestinal bacterial flora. Scandinavian Journal of Gastroenterology 5: Suppl 6 139–163
    [Google Scholar]
  33. Tabaqchali S., Wilks M., Thin R. N. 1983; Gardnerella vaginalis and anaerobic bacteria in genital disease. British Journal of Venereal Disease 59:111–115
    [Google Scholar]
  34. Taylor E., Blackwell A. L., Barlow D., Phillips L. 1982; Gardnerella vaginalis, anaerobes and vaginal discharge. Lancet 1:1376–1379
    [Google Scholar]
  35. Weinstein L. 1938; The bacterial flora of the human vagina. Yale Journal of Biological Medicine 10:247–260
    [Google Scholar]
  36. Wilks M., Thin R. N., Tabaqchali S. 1982; Quantitative methods for studies on vaginal flora. Journal of Medical Microbiology 15:141–147
    [Google Scholar]
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