SUMMARY. The relationship between vaginal carriage and subsequent neonatal acquisition of was investigated. Vaginal carriage of was detected in 11% of women attending the Department of Genital Medicine Clinic. was isolated from the vagina in 18% of 50 mothers before delivery, and 8% after delivery; 62% of their babies had positive faecal cultures. Eight of nine of the babies whose mothers had positive cultures before delivery became colonised with , while 23 of 41 babies whose mothers had negative cultures became colonised. This suggests that both the vagina and the environment may act as sources of neonatal acquisition of . Broth enrichment culture proved a more sensitive method for isolating from the vagina than direct plate culture and should be used in such investigations.


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