1887

Abstract

SUMMARY. Intraperitoneal injection of ss. into HAM/1CR mice was lethal, but viable counts of bacteria from whole body homogenates, organs and blood indicated that death was not due to sustained bacterial multiplication. Heat-killed organisms (5 x 10 cfu) injected into 7-day-old mice caused death within 24 h and this was shown to be due to endotoxin. Both ferric iron and heterologous lipopolysaccharide enhanced virulence; the LD50 was lowered from 1.8 x 10 cfu to 2.7 x10 cfu when both were used. Three-day-old or adult animals survived challenge with without clinical symptoms when challenged orally or by intravenous or intraperitoneal routes.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-18-1-27
1984-08-01
2019-10-22
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-18-1-27
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error