%0 Journal Article %A Neale, M. Lynne %A Matthewsy, N. %T Antimicrobial effects of a macrophage-derived cytotoxin from the serum of BCG-primed rabbits (tumour necrosis serum) %D 1984 %J Journal of Medical Microbiology, %V 17 %N 2 %P 211-213 %@ 1473-5644 %R https://doi.org/10.1099/00222615-17-2-211 %I Microbiology Society, %X SUMMARY Previous studies have shown that a macrophage-derived cytotoxin, found in high titre in the serum of BCG-primed rabbits, killed malarial parasites and certain tumour cells. In this study, the macrophage cytotoxin was tested for activity against microorganisms other than protozoa. No activity was seen against a range of gram-negative or gram-positive bacteria or against Candida albicans. It is concluded that the macrophage cytotoxin has limited anti-microbial activity, perhaps restricted to certain intra-cellular parasites. %U https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-17-2-211