Motile curved rods seen in vaginal secretions have been isolated on Columbia agar supplemented with 5% human blood and vitamin K. Growth occurred anaerobically and in 5% oxygen but not in more aerobic conditions. There were two distinct groups of these organisms, distinguishable by morphology, biochemical activity and susceptibility to metronidazole. All isolates were sensitive to a wide range of antimicrobial agents, with the exception of nalidixic acid and polymyxin, but one group was resistant to metronidazole. There was little difference between the results of tests of susceptibility to aminoglycosides or to metronidazole performed in anaerobic and microaerophi-lic conditions. Motile curved rods were isolated from 18 of 80 patients with a clinical diagnosis of non-specific vaginitis, but from only two of 39 without the disease.
DuerdenB. I.,
HolbrookW. P.,
ColleeJ. G.,
WattB.1976; The characterization of clinically important gram negative anaerobic bacilli by conventional bacteriological tests. Journal of Applied Bacteriology 40:163–188
LoweG. H.1962; The rapid detection of lactose fermentation in paracolon organisms by the demonstration of β-D-galactosidase. Journal of Medical Laboratory Technology 19:21–25
NarangH. K.,
CoddA. A.1979; A low-speed centrifugation technique for the preparation of grids for direct virus examination by electron microscopy. Journal of Clinical Pathology 32:304–305
PrinceH. N.,
GrunbergE.,
TitsworthE.,
DelorenzoW. F.1969; Effects of 1 – (2-nitro-1-imidazolyl)-3-methoxy-2-propanol and 2-methyl-5-nitroimidazole-1-ethanol against anaerobic and aerobic bacteria and protozoa. Applied Microbiology 18:728–730
RalphE. D.,
AmatnieksY. E.1980; Relative susceptibilities of Gardnerella vaginalis (Haemophilus vaginalis), Neisseria gonorrhoeae and Bacteroides fragilis to metronidazole and its two major metabolites. Sexually Transmitted Diseases 7:157–160
RotimiV. O.,
FaulknerJ.,
DuerdenB. I.1980; Rapid methods for identification of clinical isolates of Gram-negative anaerobic bacilli. Medical Laboratory Sciences 37:331–339
SkarinA.,
SpiegelC. A.,
WestromL.,
HolmesK. K.,
MardhP. A.1981; Demonstration of a strictly anaerobic, Gram-negative, comma-shaped bacterium in females with symptoms of lower genital tract infection. In Abstracts of 4th International Meeting on Sexually Transmitted Diseases (Heidelberg, October 18–20). p 9
SkirrowM. B.,
BenjaminJ.1982; The classification of ‘thermophilic’ Campylobacters and their distribution in man and domestic animals. In Campylobacter Epidemiology, Pathogenesis and Biochemistry 1st ed., edited by
NewelD. G.
MTP Press Ltd.; Lancaster:
SpiegelC. A.,
SkarinA.,
MardhP. A.,
HolmesK. K.1981; Isolation and characterisation of a curved motile anaerobic organism associated with non-specific vaginitis. In Abstracts of 4th International Meeting on Sexually Transmitted Diseases (Heidelberg, October 18–20). p 8
TannerA. C. R.,
BadgerS.,
LaiC. H.,
ListgartenM. A.,
ViscontiR. A.,
SocranskyS. S.1981; Wolinella gen. nov., Wolinella succinogenes (Vibrio succinogenes Wolin et al.) comb, nov., and Description of Bacteroides gracilis sp. nov., Wolinella recta sp. nov., Campylobacter conscisus sp. nov., and Eikenella corrodens from Humans with Periodontal Disease. International Journal of Systemic Bacteriology 31:432–445
ThornleyM. J.1960; The differentiation of Pseudomonas from other Gram-negative bacteria on the basis of arginine metabolism. Journal of Applied Bacteriology 23:37–52