1887

Abstract

SUMMARY

serovars and were adapted to grow in a chemically-defined, protein-free (PF) medium. Formolised monovalent vaccines of serovars and and a bivalent mixture of the two were prepared from PF cultures. Live PF cultures and the vaccine preparations retained their agglutinating antigens and their immunogenicity when tested in rabbits and guineapigs. The vaccines were not pyrogenic and dermal reactions were slight.

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/content/journal/jmm/10.1099/00222615-15-4-493
1982-11-01
2024-12-03
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