RT Journal Article SR Electronic(1) A1 LANCASTER, R. DENISE A1 COLSTON, M. J. A1 HILSON, G. R. F. A1 TURNER, SHEILA M.YR 1981 T1 The effect of body temperature and cell-mediated immunity on the growth of Mycobacterium marinum and Mycobacterium leprae in mice JF Journal of Medical Microbiology, VO 14 IS 4 SP 493 OP 500 DO https://doi.org/10.1099/00222615-14-4-493 PB Microbiology Society, SN 1473-5644, AB Summary. Evidence is presented that the high susceptibility of armadillos to infection with Mycobacterium leprae cannot be explained solely in terms of body temperature because mutant mice maintained with a body temperature similar to that of armadillos do not become heavily infected with M. leprae. The depression of cell-mediated immunity accompanying the low body temperature is not sufficient to produce an overwhelming infection. The results obtained with M. marinum suggest that whereas lack of cell-mediated immunity or a low body temperature result in a moderately enhanced infection in the mouse a combination of both of these factors is required to produce an overwhelming infection involving the internal organs., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-14-4-493