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Abstract
PLATE XL
CORYNEBACTERIUM ULCERANS, which is usually associated with mastitis in cattle, has been reported as a cause of sore throat and tonsillitis in man (Jebb, 1948; Saxholm, 1951; Tomlinson, 1966). Subcutaneous injection of this organism into guinea-pigs produces features, such as haemorrhage and oedema at the site of injection and haemorrhagic adrenals, which are characteristic of diphtheria toxin. Diphtheria antitoxin neutralises the lethal effect of toxin from some strains of C. ulcerans (Fox and Frost, 1974) but not from others (Souckova and Soucek, 1974). In this study the purification and preliminary characterisation of a toxin from C. ulcerans strain 378 is reported.
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© 1980 The Pathological Society of Great Britain and Ireland