THE OCCURRENCE of excess infant deaths during influenza epidemics (Dauer and Serfling, 1961; Wynne Griffith , 1972) suggests that influenza plays a greater role in infant death and severe illness than is generally recognised (Nelson , 1975; Paisley , 1978). Although children are highly susceptible to influenza infection, their symptoms may be milder than in the adult (Douglas, 1975). However, convulsions, croup and pneumonia also occur (Brocklebank , 1972; Naude , 1974; Spence, Brodie and Masson, 1975; Laraya-Cuasay , 1977; Paisley , 1978). The pathology of influenza in infants has rarely been reported, and then usually in cases complicated by other disease processes (Louria , 1959); by contrast, the findings in adult man (Hers and Mulder, 1961) and in the adult ferret (Francis and Stuart-Harris, 1938) have been well described.

Influenza in the healthy adult ferret is a transient, non-fatal illness, similar to that occurring in the vast majority of human adults (Toms , 1976). This similarity of clinical and pathological responses in man and ferret, and the recognition of fatal infection in the fetal ferret (Collie , 1978) stimulated the present investigation into the susceptibility of the newborn ferret to influenza.


Article metrics loading...

Loading full text...

Full text loading...


Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error