RT Journal Article SR Electronic(1) A1 Ramakrishnan, Indrani A1 Agarwal, S.C.YR 1980 T1 CELL-MEDIATED IMMUNITY IN EXPERIMENTAL PARAINFLUENZA TYPE 3 VIRUS INFECTION JF Journal of Medical Microbiology, VO 13 IS 4 SP 527 OP 534 DO https://doi.org/10.1099/00222615-13-4-527 PB Microbiology Society, SN 1473-5644, AB SUMMARY Local respiratory-tract infection was produced experimentally in guinea-pigs by intranasal instillation of a suspension of parainfluenza virus type 3. Histologically, interstitial pneumonitis developed within 10 days and persisted for at least 70 days. Cell-mediated immunity was measured at intervals for 70 days after infection. Dermal reactivity could not be elicited. Leucocyte-migration inhibition and macrophage-migration inhibition were increased. Macrophage aggregation was present. Increased cell-mediated immunity could be transferred from infected donor animals to normal recipient animals by adoptive spleen-cell transfer even 60 and 70 days after infection., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-13-4-527