1887

Abstract

Summary

A large molecular-weight fraction of culture filtrate protected rats and mice against a lethal infection with a heterologous serotype, and to some extent against and The active components were obtained from cultures grown for several days in a simple synthetic medium. Infection and vaccination with serotype 16 induced agglutinating and precipitating antibodies to the components of this serotype only; in rats infected or vaccinated with serotype 1, low titres of agglutinating antibody against type 16 were found. Vaccine prepared from type 1 or 16 increased, within 3 days of infection, the resistance of rats to type-16 organisms; within the same period agglutinins or precipitins were not produced. It is possible that the protection was based on opsonic and antitoxic activities.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-13-2-201
1980-05-01
2019-12-14
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-13-2-201
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error