THE HORNY layer of epidermis, which can be colonised by dermatophytes, is covered by surface lipids. The lipolytic activity of dermatophytes may therefore be of particular importance in the early stages of infection, before the fungus has established permanent contact with keratin; but little is known about the possible presence of lipases in these pathogenic fungi. The early observations of Mallinckrodt-Haupt (1927), Tate (1929), Nékám (1935) and, more recently, Pinetti and Lostia (1961) and Böhme (1969) have demonstrated that dermatophytes can hydrolyse lipids of animal and of vegetable origin. The occurrence of lipase has been demonstrated histochemically (Knight, 1957) and in dermatophyte mycelial filtrates (Böhme, 1969). This paper describes the screening of the more common dermatophytes to test for the presence of lipases.


Article metrics loading...

Loading full text...

Full text loading...


  1. Böhme H. 1969; Vergleichende Untersuchungen an Dermatophyten und anderen keratino-philen Pilzen fiber Wachstum, Stoffwechsel und Enzymausscheidung mit Lipiden als Hauptkohlenstoffquellen. Thesis, Halle/Saale
  2. Dinh-Nguyen Ng, Vincent J. 1972; A simple monospore selector. Mykosen 15:343
    [Google Scholar]
  3. Kendall M. G. 1948; Rank correlation methods. Griffin: London:
    [Google Scholar]
  4. Knight S. G. 1957; The mechanism of triglyceride therapy in dermatomycoses. J. invest. Derm 28:363
    [Google Scholar]
  5. Mallinckrodt-Haupt A. Von. 1927; Der Fettstoffwechsel der Hautpilze. Das Fettspaltungs-vermogen der lebenden Pilzkultur. Zentbl. Bakt. ParasitKde I. Abt. Orig 103:73
    [Google Scholar]
  6. Nekam L. Jr 1935; Uber den quantitativen Fermentgehalt der Parasitaren und Hautpatho-genen Pilze. Z. ParasitKde 8:121
    [Google Scholar]
  7. Pinetti P., Lostia A. 1961; Contribute allo studio delle lipasi dermatomicetiche. Rass. med. Sarda 63:355
    [Google Scholar]
  8. Siegel S. 1956; Nonparametric statistics for the behavioral sciences. McGraw-Hill New York, Toronto, London:
    [Google Scholar]
  9. Tate P. 1929; On the enzymes of certain dermatophytes or ringworm fungi. Parasitology 21:31
    [Google Scholar]
  10. Ullmann U., Blasius C. 1974; Ein modifiziertes, einfaches Verfahren zur Bestimmung der unterschiedlichen lipolytischen Aktivitaten von Mikroorganismen. Zentbl. Bakt. ParasitKde I. Abt. Orig A229:264
    [Google Scholar]
  11. Vincent J. 1972; Mycelial suspensions prepared ultrasonically. Experientia 28:722
    [Google Scholar]
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error