1887

Abstract

Summary

Electronmicrographs of sections show that the L-phases var. (Benedek) simulate the various types of microorganism described by previous workers as associated with ostensibly non-infective conditions, notably cancer and arthritis; mycoplasmas, myco-bacteria, corynebacteria and actinomycetes. The stages of the L-cycle, from spheroplasts through smaller and larger ‘diphtheroid’ bacteria to the fully reverted sporogenous bacillus, differ from one another mainly in their degree of reconstitution of the cell envelopes. Occurrence in ‘diphtheroids’ of non-resistant, cell-wall-deficient spore-like bodies, confirms their relationship with the true sporing bacillus stage. Large, swollen forms appear to be mother cells of minute stages.

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/content/journal/jmm/10.1099/00222615-12-4-469
1979-11-01
2024-04-19
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References

  1. Balassa G., Milhaud P., Sousa J. C. F., Silva M. T. 1979; Decadent sporulation mutants of Bacillus subtilis. J. gen. Microbiol 110:381
    [Google Scholar]
  2. Bartlett R., Bisset K. A. 1979; Induction of reversion from the L-form to the sporo-genous phase of Bacillus licheniformis var. endoparasiticus (Benedek). J. med. Microbiol 12:239
    [Google Scholar]
  3. Bisset K. A. 1952; Complete and reduced life cycles in Rhizobium. J. gen Microbiol 7:233
    [Google Scholar]
  4. Bisset K. A. 1970 The cytology and life-history of bacteria 3rd ed Edinburgh: pp. 13-15 and 89-91
    [Google Scholar]
  5. Bisset K. A. 1977; Isolations of micro-organisms from arthritic patients and healthy normals. Am. rheum. Dis. 36:96
    [Google Scholar]
  6. Bisset K. A., Bartlett R. 1978; The isolation and characters of L-forms and reversions of Bacillus licheniformis var. endoparasiticus (Benedek) associated with the erythrocytes of clinically normal persons. J. med. Microbiol 11:335
    [Google Scholar]
  7. Brehmer von W. 1934; “Siphonospora polymorpha” n.sp. ein neuer Mikroorganismus des Blutes und seine Beziehung ziir Turmorgenese. Medsche Welt, Berl 8:1179
    [Google Scholar]
  8. Gillberg B. O. 1969; Heat resistance and pigmented variants of Rhizobium. Nature, Lond 222:574
    [Google Scholar]
  9. Glauert A. M. 1974; Practical methods in electron microscopy. Amsterdam vol 3: p W3
    [Google Scholar]
  10. Glover T. J. 1930; The bacteriology of cancer. Can. Lancet Pract 74:92
    [Google Scholar]
  11. Mattman L. H. 1974; Cell wall deficient forms. Cleveland, Ohio pp. 381-383
    [Google Scholar]
  12. Pease P. 1970; Microorganisms associated with malignancy. Ann. N. Y. Acad. Sci part IV, discussion 174:782
    [Google Scholar]
  13. Pease P. 1974; Identification of bacteria from blood and joint fluids of human subjects as Bacillus licheniformis. Ann. rheum. Dis 33:67
    [Google Scholar]
  14. Reynolds E. S. 1963; The use of lead citrate at high pH as an electron opaque stain in electron microscopy. J. cell Biol 17:208
    [Google Scholar]
  15. Roberts D. H. 1964; L-phase bacterial forms associated with infectious synovitis in chickens and turkeys. Res. vet. Sci 5:441
    [Google Scholar]
  16. Schaeffer A. B., Fulton M. 1933; A simplified method of staining endospores. Science, N.Y 77:194
    [Google Scholar]
  17. Symposiumm 1970; Microorganisms associated with malignancy, part IV. Ann. N. Y. Acad. Sci 174:636
    [Google Scholar]
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