1887

Abstract

Summary

A unique and characteristic bacteriocine-like inhibitor elaborated by M-type 4, T-pattern 4, group-A streptococci was isolated and partially purified. This inhibitor was found to be produced optimally in Todd-Hewitt broth; after extraction and concentration, was shown to be protein in nature, and to have a m.w. of 8000. It was extremely heat stable and acid tolerant, but was quickly inactivated in alkaline conditions. It could be demonstrated in cell-bound form, but 99·5% was found in culture supernates. It was specifically adsorbed by viable sensitive cells, and its mode of action was bacteristatic.

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/content/journal/jmm/10.1099/00222615-12-4-413
1979-11-01
2019-10-18
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-12-4-413
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