1887

Abstract

SUMMARY

Three capsulate pneumococcal strains of serotypes 1, 2 and 3, and one non-capsulate strain of serotype 47, were found to activate human complement by the alternative pathway to a similar extent over the concentration range examined. Nevertheless, the capsulate strains, in contrast to the non-capsulate, are known to require complement attachment for phagocytosis and it is therefore postulated that the toxic by-products released cause the wave of oedema characteristic of pneumococcal lobar pneumonia.

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/content/journal/jmm/10.1099/00222615-11-1-7
1978-02-01
2019-10-19
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http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-11-1-7
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