@article{mbs:/content/journal/jmm/10.1099/00222615-10-1-43, author = "Skidmore, Susan J. and Boxall, Elizabeth H.", title = "Small Virus Particles in Faeces of Patients with Infectious Hepatitis (Hepatitis A)", journal= "Journal of Medical Microbiology", year = "1977", volume = "10", number = "1", pages = "43-48", doi = "https://doi.org/10.1099/00222615-10-1-43", url = "https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-10-1-43", publisher = "Microbiology Society", issn = "1473-5644", type = "Journal Article", abstract = "SUMMARY Forty-one faecal samples from infectious-hepatitis patients and their contacts were investigated for the presence of hepatitis-A-associated viral particles. Of these, 16 gave a positive result by immune electronmicroscopy or caesium-chloride density-gradient centrifugation. The latter method proved invaluable in detecting small numbers of virus particles. The particles found had a buoyant density of 1.34−1.35 and a size range of 21-28 nm. Epidemio-logical evidence suggested that they might be the causative agent of hepatitis A.", }