@article{mbs:/content/journal/jmm/10.1099/00222615-1-1-145, author = "POREBSKA, ALICJA and PEREIRA, H. G. and ARMSTRONG, J. A.", title = "Cytoplasmic inclusions and nuclear changes in cells infected with influenza-B viruses (Plate XII)", journal= "Journal of Medical Microbiology", year = "1968", volume = "1", number = "1", pages = "145-151", doi = "https://doi.org/10.1099/00222615-1-1-145", url = "https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-1-1-145", publisher = "Microbiology Society", issn = "1473-5644", type = "Journal Article", abstract = "Summary Basophilic cytoplasmic inclusions, often accompanied by nuclear changes, develop regularly in primary monkey kidney cell cultures infected with influenza-B viruses. The inclusions stain positively for RNA, and electron microscopy shows them to contain large aggregates of ribosome-like particles. Inclusions form late in the infection, and it has not been possible to correlate them with the synthesis of virus-specific antigens. The capacity of influenza-B virus to give rise to inclusions is specifically neutralised by virus antibody. The inclusions seem to be a useful character for the distinction of influenza-B strains from other haemadsorbing viruses.", }