1887

Abstract

Summary

Basophilic cytoplasmic inclusions, often accompanied by nuclear changes, develop regularly in primary monkey kidney cell cultures infected with influenza-B viruses. The inclusions stain positively for RNA, and electron microscopy shows them to contain large aggregates of ribosome-like particles. Inclusions form late in the infection, and it has not been possible to correlate them with the synthesis of virus-specific antigens. The capacity of influenza-B virus to give rise to inclusions is specifically neutralised by virus antibody. The inclusions seem to be a useful character for the distinction of influenza-B strains from other haemadsorbing viruses.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-1-1-145
1968-08-01
2022-01-26
Loading full text...

Full text loading...

References

  1. Armstrong J. A., Hopper P. K. 1959 Expl Cell Res 16:584
    [Google Scholar]
  2. Berkaloff A., Colobert L. 1963 Microscopie 2:433
    [Google Scholar]
  3. Berkaloff A., Stussi T., Colobert L. 1962 Ibid 1:351
    [Google Scholar]
  4. Brandt C.D. 1961 Virology 14:1
    [Google Scholar]
  5. Coackley W., Pini A. 1965 J. Path. Bact 90:672
    [Google Scholar]
  6. Finter N.B. 1964 Virology 24:589
    [Google Scholar]
  7. Harwin R. M., Joostting A., Gear J. H. S. 1966 Lancet 1:1218
    [Google Scholar]
  8. Lief  , Florence S., Henle W. 1959 Bull. Wld Hlth Org 20:411
    [Google Scholar]
  9. Millonig G. 1961 J. Appi. Phys 32:1637
    [Google Scholar]
  10. Mogabgab W. J., Green I. J., Dier-Khising O.C., Phillips I. A. 1955Proc. Soc. Exp. Biol. Med 89:654
    [Google Scholar]
  11. Morgan C., Rose H. M., Moore D. H. 1956 J. Exp. Med 104:171
    [Google Scholar]
  12. Morgan J. F., Morton  , Helen J., Parker R. C. 1950Proc. Soc. Exp. Biol. Med 73:1
    [Google Scholar]
  13. Niven  , Janet S. F., Armstrong J. A., Balfour  , Brigid M., Klemperer H. G., Tyrrell D. A. J. 1962 J. Path. Bact 84:1
    [Google Scholar]
  14. Pereira H. G., Pereira  , Marguerite S., Law V. G. 1964 Bull. WldHlth Org 31:129
    [Google Scholar]
  15. Termeulen V., Love R. 1967 J.Virol. 1:626
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-1-1-145
Loading

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error