RT Journal Article SR Electronic(1) A1 SMITH-PALMER, A. A1 STEWART, J. A1 FYFE, L.YR 2002 T1 Inhibition of listeriolysin O and phosphatidylcholine-specific production in Listeria monocytogenes by subinhibitory concentrations of plant essential oils JF Journal of Medical Microbiology, VO 51 IS 7 SP 567 OP 608 DO https://doi.org/10.1099/0022-1317-51-7-567 PB Microbiology Society, SN 1473-5644, AB Successful infection by Listeria monocytogenes is dependent upon a range of bacterial extracellular proteins including a cytolysin termed listeriolysin O and phosphatidylcholine-specific phospholipase C. Five plant essential oils – bay, clove, cinnamon, nutmeg and thyme – significantly reduced the production of listeriolysin O by L. monocytogenes. The greatest change was observed after culture with oil of thyme, which reduced haemolysis to 52.1 haemolytic units (HU)/ml compared with 99.85muHU/ml observed with the control. Oil of clove was the only oil that also significantly reduced phosphatidylcholine-specific phospholipase C activity. These changes were observed despite the oils causing no change to the final bacterial concentration or total extracellular protein concentration., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/0022-1317-51-7-567