1887

Abstract

Papillomaviruses are a group of ubiquitous viruses that are often found in normal skin of humans, as well as a range of different vertebrates. In this study, swab samples collected from the healthy skin of 225 Australian animals from 54 species were analysed for the presence of papillomavirus DNA with the general skin papillomavirus primer pair FAP59/FAP64. A total of five putative and potential new animal papillomavirus types were identified from three different animal species. The papillomaviruses were detected in one monotreme and two marsupial species: three from koalas, and one each from an Eastern grey kangaroo and an echidna. The papillomavirus prevalence in the three species was 14 % (10/72) in koalas, 20 % (1/5) in echidnas and 4 % (1/23) in Eastern grey kangaroos. Phylogenetic analysis was performed on the putative koala papillomavirus type that could be cloned and it appears in the phylogenetic tree as a novel putative papillomavirus genus. The data extend the range of species infected by papillomaviruses to the most primitive mammals: the monotremes and the marsupials.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/vir.0.82195-0
2006-11-01
2019-11-18
Loading full text...

Full text loading...

/deliver/fulltext/jgv/87/11/3195.html?itemId=/content/journal/jgv/10.1099/vir.0.82195-0&mimeType=html&fmt=ahah

References

  1. Antonsson, A. & Hansson, B. G. ( 2002; ). Healthy skin of many animal species harbors papillomaviruses which are closely related to their human counterparts. J Virol 76, 12537–12542.[CrossRef]
    [Google Scholar]
  2. Antonsson, A., Forslund, O., Ekberg, H., Sterner, G. & Hansson, B. G. ( 2000; ). The ubiquity and impressive genomic diversity of human skin papillomaviruses suggest a commensalic nature of these viruses. J Virol 74, 11636–11641.[CrossRef]
    [Google Scholar]
  3. Antonsson, A., Erfurt, C., Hazard, K., Holmgren, V., Simon, M., Kataoka, A., Hossain, S., Håkangård, C. & Hansson, B. G. ( 2003a; ). Prevalence and type spectrum of human papillomaviruses in healthy skin samples collected in three continents. J Gen Virol 84, 1881–1886.[CrossRef]
    [Google Scholar]
  4. Antonsson, A., Karanfilovska, S., Lindqvist, P. G. & Hansson, B. G. ( 2003b; ). General acquisition of human papillomavirus infections of skin occurs in early infancy. J Clin Microbiol 41, 2509–2514.[CrossRef]
    [Google Scholar]
  5. Bernard, H. U. ( 1994; ). Coevolution of papillomaviruses with human populations. Trends Microbiol 2, 140–143.[CrossRef]
    [Google Scholar]
  6. Chan, S. Y., Bernard, H. U., Ratterree, M., Birkebak, T. A., Faras, A. J. & Ostrow, R. S. ( 1997; ). Genomic diversity and evolution of papillomaviruses in rhesus monkeys. J Virol 71, 4938–4943.
    [Google Scholar]
  7. de Villiers, E.-M. ( 2001; ). Taxonomic classification of papillomaviruses. Papillomavirus Rep 12, 57–63.
    [Google Scholar]
  8. de Villiers, E. M., Fauquet, C., Broker, T. R., Bernard, H. U. & zur Hausen, H. ( 2004; ). Classification of papillomaviruses. Virology 324, 17–27.[CrossRef]
    [Google Scholar]
  9. Felsenstein, J. ( 1982; ). Numerical methods for inferring evolutionary trees. Q Rev Biol 57, 379–404.[CrossRef]
    [Google Scholar]
  10. Felsenstein, J. ( 1985; ). Confidence limits on phylogenies: an approach using the bootstrap. Evolution 39, 783–791.[CrossRef]
    [Google Scholar]
  11. Forslund, O., Antonsson, A., Nordin, P., Stenquist, B. & Hansson, B. G. ( 1999; ). A broad range of human papillomavirus types detected with a general PCR method suitable for analysis of cutaneous tumours and normal skin. J Gen Virol 80, 2437–2443.
    [Google Scholar]
  12. Ghim, S. J., Rector, A., Delius, H., Sundberg, J. P., Jenson, A. B. & Van Ranst, M. ( 2004; ). Equine papillomavirus type 1: complete nucleotide sequence and characterization of recombinant virus-like particles composed of the EcPV-1 L1 major capsid protein. Biochem Biophys Res Commun 324, 1108–1115.[CrossRef]
    [Google Scholar]
  13. Jeanmougin, F., Thompson, J. D., Gouy, M., Higgins, D. G. & Gibson, T. J. ( 1998; ). Multiple sequence alignment with Clustal X. Trends Biochem Sci 23, 403–405.[CrossRef]
    [Google Scholar]
  14. Nicholas, K. B., Nicholas, H. B., Jr & Deerfield, D. W. ( 1997; ). Genedoc: analysis and visualization of genetic variation. EMBNEW News 4, 14.
    [Google Scholar]
  15. Perrott, M. R., Meers, J., Greening, G. E., Farmer, S. E., Lugton, I. W. & Wilks, C. R. ( 2000; ). A new papillomavirus of possums (Trichosurus vulpecula) associated with typical wart-like papillomas. Arch Virol 145, 1247–1255.[CrossRef]
    [Google Scholar]
  16. Rector, A., Bossart, G. D., Ghim, S. J., Sundberg, J. P., Jenson, A. B. & Van Ranst, M. ( 2004; ). Characterization of a novel close-to-root papillomavirus from a Florida manatee by using multiply primed rolling-circle amplification: Trichechus manatus latirostris papillomavirus type 1. J Virol 78, 12698–12702.[CrossRef]
    [Google Scholar]
  17. Rector, A., Tachezy, R., Van Doorslaer, K., MacNamara, T., Burk, R. D., Sundberg, J. P. & Van Ranst, M. ( 2005a; ). Isolation and cloning of a papillomavirus from a North American porcupine by using multiply primed rolling-circle amplification: the Erethizon dorsatum papillomavirus type 1. Virology 331, 449–456.[CrossRef]
    [Google Scholar]
  18. Rector, A., Van Doorslaer, K., Bertelsen, M., Barker, I. K., Olberg, R. A., Lemey, P., Sundberg, J. P. & Van Ranst, M. ( 2005b; ). Isolation and cloning of the raccoon (Procyon lotor) papillomavirus type 1 by using degenerate papillomavirus-specific primers. J Gen Virol 86, 2029–2033.[CrossRef]
    [Google Scholar]
  19. Shadan, F. F. & Villarreal, L. P. ( 1993; ). Coevolution of persistently infecting small DNA viruses and their hosts linked to host-interactive regulatory domains. Proc Natl Acad Sci U S A 90, 4117–4121.[CrossRef]
    [Google Scholar]
  20. Sundberg, J. P. ( 1987; ). Papillomavirus infections in animals. In Papillomaviruses and Human Disease, pp. 40–103. Edited by K. Syrjänen, L. Gissmann & L. G. Koss. Berlin: Springer.
  21. Tachezy, R., Duson, G., Rector, A., Jenson, A. B., Sundberg, J. P. & Van Ranst, M. ( 2002a; ). Cloning and genomic characterization of Felis domesticus papillomavirus type 1. Virology 301, 313–321.[CrossRef]
    [Google Scholar]
  22. Tachezy, R., Rector, A., Havelkova, M., Wollants, E., Fiten, P., Opdenakker, G., Jenson, B., Sundberg, J. & Van Ranst, M. ( 2002b; ). Avian papillomaviruses: the parrot Psittacus erithacus papillomavirus (PePV) genome has a unique organization of the early protein region and is phylogenetically related to the chaffinch papillomavirus. BMC Microbiol 2, 19.[CrossRef]
    [Google Scholar]
  23. Van Doorslaer, K., Rector, A., Vos, P. & Van Ranst, M. ( 2006; ). Genetic characterization of the Capra hircus papillomavirus: a novel close-to-root artiodactyl papillomavirus. Virus Res 118, 164–169.[CrossRef]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/vir.0.82195-0
Loading
/content/journal/jgv/10.1099/vir.0.82195-0
Loading

Data & Media loading...

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error