Effective treatment of retrovirus-induced suppression of antibody responses with CpG oligodeoxynucleotides

References

1. Chesebro, B., Miyazawa, M. & Britt, W. J. ( 1990; ). Host genetic control of spontaneous and induced immunity to Friend murine retrovirus infection. Annu Rev Immunol 8, 477–499.[CrossRef]
   [Google Scholar]
2. Dittmer, U., Race, B., Peterson, K. E., Stromnes, I. M., Messer, R. J. & Hasenkrug, K. J. ( 2002; ). Essential roles for CD8+ T cells and gamma interferon in protection of mice against retrovirus-induced immunosuppression. J Virol 76, 450–454.[CrossRef]
   [Google Scholar]
3. Equils, O., Schito, M. L., Karahashi, H., Madak, Z., Yarali, A., Michelsen, K. S., Sher, A. & Arditi, M. ( 2003; ). Toll-like receptor 2 (TLR2) and TLR9 signaling results in HIV-long terminal repeat trans-activation and HIV replication in HIV-1 transgenic mouse spleen cells: implications of simultaneous activation of TLRs on HIV replication. J Immunol 170, 5159–5164.[CrossRef]
   [Google Scholar]
4. Faxvaag, A., Espevik, T. & Dalen, A. ( 1995; ). An immunosuppressive murine leukaemia virus induces a Th1→Th2 switch and abrogates the IgM antibody response to sheep erythrocytes by suppressing the production of IL-2. Clin Exp Immunol 102, 487–495.
   [Google Scholar]
5. Hasenkrug, K. J., Brooks, D. M. & Dittmer, U. ( 1998; ). Critical role for CD4⁺ T cells in controlling retrovirus replication and spread in persistently infected mice. J Virol 72, 6559–6564.
   [Google Scholar]
6. Hornung, V., Rothenfusser, S., Britsch, S., Krug, A., Jahrsdorfer, B., Giese, T., Endres, S. & Hartmann, G. ( 2002; ). Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 168, 4531–4537.[CrossRef]
   [Google Scholar]
7. Kabat, D. ( 1989; ). Molecular biology of Friend viral erythroleukemia. Curr Top Microbiol Immunol 148, 1–42.
   [Google Scholar]
8. Krieg, A. M. ( 2001; ). Now I know my CpGs. Trends Microbiol 9, 249–252.[CrossRef]
   [Google Scholar]
9. Krieg, A. M., Yi, A. K., Matson, S., Waldschmidt, T. J., Bishop, G. A., Teasdale, R., Koretzky, G. A. & Klinman, D. M. ( 1995; ). CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374, 546–549.[CrossRef]
   [Google Scholar]
10. Olbrich, A. R. M., Schimmer, S., Heeg, K., Schepers, K., Schumacher, T. N. & Dittmer, U. ( 2002; ). Effective postexposure treatment of retrovirus-induced disease with immunostimulatory DNA containing CpG motifs. J Virol 76, 11397–11404.[CrossRef]
    [Google Scholar]
11. Olbrich, A. R. M., Schimmer, S. & Dittmer, U. ( 2003; ). Preinfection treatment of resistant mice with CpG oligodeoxynucleotides renders them susceptible to Friend retrovirus-induced leukemia. J Virol 77, 10658–10662.[CrossRef]
    [Google Scholar]
12. Scheller, C., Ullrich, A., McPherson, A. & 10 other authors ( 2004; ). CpG oligodeoxynucleotides activate HIV replication in latently infected human T cells. J Biol Chem 279, 21897–21902.[CrossRef]
    [Google Scholar]
13. Schlaepfer, E., Audige, A., von Beust, B., Manolova, V., Weber, M., Joller, H., Bachmann, M. F., Kundig, T. M. & Speck, R. F. ( 2004; ). CpG oligodeoxynucleotides block human immunodeficiency virus type 1 replication in human lymphoid tissue infected ex vivo. J Virol 78, 12344–12354.[CrossRef]
    [Google Scholar]
14. Stromnes, I. M., Dittmer, U., Schumacher, T. N., Schepers, K., Messer, R. J., Evans, L. H., Peterson, K. E., Race, B. & Hasenkrug, K. J. ( 2002; ). Temporal effects of gamma interferon deficiency on the course of Friend retrovirus infection in mice. J Virol 76, 2225–2232.[CrossRef]
    [Google Scholar]
15. Sun, S., Kishimoto, H. & Sprent, J. ( 1998; ). DNA as an adjuvant: capacity of insect DNA and synthetic oligodeoxynucleotides to augment T cell responses to specific antigen. J Exp Med 187, 1145–1150.[CrossRef]
    [Google Scholar]
16. Teleshova, N., Kenney, J., Jones, J. & 7 other authors ( 2004; ). CpG-C immunostimulatory oligodeoxyribonucleotide activation of plasmacytoid dendritic cells in rhesus macaques to augment the activation of IFN-gamma-secreting simian immunodeficiency virus-specific T cells. J Immunol 173, 1647–1657.[CrossRef]
    [Google Scholar]
17. Verthelyi, D., Gursel, M., Kenney, R. T., Lifson, J. D., Liu, S., Mican, J. & Klinman, D. M. ( 2003; ). CpG oligodeoxynucleotides protect normal and SIV-infected macaques from Leishmania infection. J Immunol 170, 4717–4723.[CrossRef]
    [Google Scholar]
18. Verthelyi, D., Wang, V. W., Lifson, J. D. & Klinman, D. M. ( 2004; ). CpG oligodeoxynucleotides improve the response to hepatitis B immunization in healthy and SIV-infected rhesus macaques. AIDS 18, 1003–1008.[CrossRef]
    [Google Scholar]
19. Walker, P. S., Scharton-Kersten, T., Krieg, A. M., Love-Homan, L., Rowton, E. D., Udey, M. C. & Vogel, J. C. ( 1999; ). Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms. Proc Natl Acad Sci U S A 96, 6970–6975.[CrossRef]
    [Google Scholar]
20. Yamamoto, S., Yamamoto, T., Shimada, S., Kuramoto, E., Yano, O., Kataoka, T. & Tokunaga, T. ( 1992; ). DNA from bacteria, but not from vertebrates, induces interferons, activates natural killer cells and inhibits tumor growth. Microbiol Immunol 36, 983–997.[CrossRef]
    [Google Scholar]