1887

Abstract

The nucleotide sequence of a novel icosahedral DNA virus infecting has been determined. The genome is 5039 nt long and includes inverted terminal repeats of 200 nt containing 131 nt long J-shaped terminal hairpins. The ‘plus' strand of the genome contains three large open reading frames (ORFs), the left and the mid-ORFs (within the left ORF) in the left-half encoding the non-structural proteins and the right ORF in the right-half encoding viral capsid proteins. NS1 protein contains conserved replication initiation and DNA-dependent ATPase/helicase domains. VP1 protein contains a conserved PGY and phospholipase A2 motifs and shows high identities with VPs of densovirus and densovirus-1 belonging to the genus . Phylogenetic analysis also revealed that this virus is most closely related to densovirus and densovirus-1. Consequently, this virus was considered as a new third member of the genus of the subfamily , and designated densovirus.

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2005-08-01
2019-11-21
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References

  1. Afanasiev, B. N., Galyov, E. E., Buchatsky, L. P. & Kozlov, Y. V. ( 1991; ). Nucleotide sequence and genomic organization of Aedes densonucleosis virus. Virology 185, 323–336.[CrossRef]
    [Google Scholar]
  2. Afanasiev, B. N., Kozlov, Y. V., Carlson, J. O. & Beaty, B. J. ( 1994; ). Densovirus of Aedes aegypti as an expression vector in mosquito cells. Exp Parasitol 79, 322–339.[CrossRef]
    [Google Scholar]
  3. Bergoin, M. & Tijssen, P. ( 1998; ). Biological and molecular propensities of densoviruses and their use in protein expression and biological control. In The Insect Viruses, pp. 141–169. Edited by L. K. Miller & L. A. Ball. New York: Plenum.
  4. Berns, K. I., Bergoin, M., Bloom, M., Muzyczka, N., Tal, J. & Tattersall, P. ( 2000; ). Family Parvoviridae. In Virus Taxonomy: Seventh Report of the International Committee on Taxonomy of Viruses, pp. 311–323. Edited by M. H. V. van Regenmortel, C. M. Fauquet, D. H. L. Bishop E. B. Carstens, M. K. Estes, S. M. Lemon, J. Maniloff, M. A. Mayo, D. J. McGeoch, C. R. Pringle & R. B. Wickner. San Diego: Academic Press.
  5. Birnstiel, M. L., Busslinger, M. & Strub, K. ( 1985; ). Transcription termination and 3′ processing: the end is in site! Cell 41, 349–359.[CrossRef]
    [Google Scholar]
  6. Boublik, Y., Jousset, F. X. & Bergoin, M. ( 1994; ). Complete nucleotide sequence and genomic organization of the Aedes albopictus parvovirus (AaPV) pathogenic for Aedes aegypti larvae. Virology 200, 752–763.[CrossRef]
    [Google Scholar]
  7. Cherbas, L. & Cherbas, P. ( 1993; ). The arthropod initiator: the capsite consensus plays an important role in transcription. Insect Biochem Mol Biol 23, 81–90.[CrossRef]
    [Google Scholar]
  8. Ding, C.-T., Urabe, M., Bergoin, M. & Kotin, R. M. ( 2002; ). Biochemical characterization of Junonia coenia densovirus nonstructural protein NS-1. J Virol 76, 338–345.[CrossRef]
    [Google Scholar]
  9. Dumas, B., Jourdan, M., Pascaud, A. M. & Bergoin, M. ( 1992; ). Complete nucleotide sequence of the cloned infectious genome of Junonia coenia densovirus reveals an organization unique among parvoviruses. Virology 191, 202–222.[CrossRef]
    [Google Scholar]
  10. Fédière, G., Li, Y., Zádori, Z., Szelei, J. & Tijssen, P. ( 2002; ). Genome organization of Casphalia extranea densovirus, a new Iteravirus. Virology 292, 299–308.[CrossRef]
    [Google Scholar]
  11. Fédière, G., El-Far, M., Li, Y., Bergoin, M. & Tijssen, P. ( 2004; ). Expression strategy of densonucleosis virus from Mythimna loreyi. Virology 320, 181–189.[CrossRef]
    [Google Scholar]
  12. Girod, A., Wobus, C. E., Zádori, Z., Ried, M., Leike, K., Tijssen, P., Kleinschmidt, J. A. & Hallek, M. ( 2002; ). The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity. J Gen Virol 83, 973–978.
    [Google Scholar]
  13. Guo, H., Zhang, J. & Hu, Y. ( 2000; ). Complete sequence and organization of Periplaneta fuliginosa densovirus genome. Acta Virol 44, 315–322.
    [Google Scholar]
  14. Ilyina, T. V. & Koonin, E. V. ( 1992; ). Conserved sequence motifs in the initiator proteins for rolling circle DNA replication encoded by diverse replicons from eubacteria, eucaryotes and archaebacteria. Nucleic Acids Res 20, 3279–3285.[CrossRef]
    [Google Scholar]
  15. Jousset, F.-X., Baquerizo, E. & Bergoin, M. ( 2000; ). A new densovirus isolated from the mosquito Culex pipiens (Diptera: Culicidae). Virus Res 67, 11–16.[CrossRef]
    [Google Scholar]
  16. Koonin, E. V. ( 1993; ). A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication. Nucleic Acids Res 21, 2541–2547.[CrossRef]
    [Google Scholar]
  17. Kozak, M. ( 1987; ). An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res 15, 8125–8148.[CrossRef]
    [Google Scholar]
  18. Kozak, M. ( 1999; ). Initiation of translation in prokaryotes and eukaryotes. Gene 234, 187–208.[CrossRef]
    [Google Scholar]
  19. Kutach, A. K. & Kadonaga, J. T. ( 2000; ). The downstream promoter element DPE appears to be as widely used as the TATA box in Drosophila core promoters. Mol Cell Biol 20, 4754–4764.[CrossRef]
    [Google Scholar]
  20. Li, Y., Zádori, Z., Bando, H., Dubuc, R., Fédière, G., Szelei, J. & Tijssen, P. ( 2001; ). Genome organization of densovirus from Bombyx mori (BmDNV-1) and enzyme activity of its capsid. J Gen Virol 82, 2821–2825.
    [Google Scholar]
  21. Lim, C. Y., Santoso, B., Boulay, T., Dong, E., Ohler, U. & Kadonaga, J. T. ( 2004; ). The MTE, a new core promoter element for transcription by RNA polymerase II. Genes Dev 18, 1606–1617.[CrossRef]
    [Google Scholar]
  22. Mayo, M. A. ( 2005; ). Changes to virus taxonomy 2004. Arch Virol 150, 189–198.[CrossRef]
    [Google Scholar]
  23. Nüesch, J. P., Cotmore, S. F. & Tattersall, P. ( 1995; ). Sequence motifs in the replicator protein of parvovirus MVM essential for nicking and covalent attachment to the viral origin: identification of the linking tyrosine. Virology 209, 122–135.[CrossRef]
    [Google Scholar]
  24. Ohler, U., Liao, G., Niemann, H. & Rubin, G. M. ( 2002; ). Computational analysis of core promoters in the Drosophila genome. Genome Biol 3, 1–12.
    [Google Scholar]
  25. Purnell, B. A., Emanuel, P. A. & Gilmour, D. S. ( 1994; ). TFIID sequence recognition of the initiation and sequences farther downstream in Drosophila class II genes. Genes Dev 8, 830–842.[CrossRef]
    [Google Scholar]
  26. Tijssen, P. & Bergoin, M. ( 1995; ). Densonucleosis viruses constitute an increasingly diversified subfamily among the parvoviruses. Semin Virol 6, 347–355.[CrossRef]
    [Google Scholar]
  27. Tijssen, P., Li, Y., El-Far, M., Szelei, J., Letarte, M. & Zádori, Z. ( 2003; ). Organization and expression strategy of ambisense genome of densonucleosis virus of Galleria mellonella. J Virol 77, 10357–10365.[CrossRef]
    [Google Scholar]
  28. Ward, T. W., Kimmick, M. W., Afanasiev, B. N. & Carlson, J. O. ( 2001; ). Characterization of the structural gene promoter of Aedes aegypti densovirus. J Virol 75, 1325–1331.[CrossRef]
    [Google Scholar]
  29. Zádori, Z., Szelei, J., Lacoste, M.-C., Li, Y., Gariépy, S., Raymond, P., Allaire, M., Nabi, I. R. & Tijssen, P. ( 2001; ). A viral phospholipase A2 is required for parvovirus infectivity. Dev Cell 1, 291–302.[CrossRef]
    [Google Scholar]
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