A novel simian immunodeficiency virus isolated from a Schmidt's guenon () Free

Abstract

A novel simian immunodeficiency virus (SIV) was characterized from a Schmidt's guenon (), which was housed in a local zoo. The virus infection was detected during a routine serological screening for antibodies that were cross-reactive with SIVmac antigens. Infection with an immunodeficiency virus was confirmed using an INNO-LIA HIV Confirmation assay. Using DNA isolated from a blot clot, a 1895 nt partial sequence was amplified and sequenced. Phylogenetic analysis showed that this virus, designated SIVschm, shares a distant relationship with SIVgsn, isolated from greater spot-nosed monkeys, and is one of the most divergent SIVs identified to date.

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/content/journal/jgv/10.1099/vir.0.19427-0
2004-01-01
2024-03-29
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References

  1. Clewley J. P., Lewis J. C., Brown D. W., Gadsby E. L. 1998; A novel simian immunodeficiency virus (SIVdrl) pol sequence from the drill monkey, Mandrillus leucophaeus . J Virol 72:10305–10309
    [Google Scholar]
  2. Courgnaud V., Pourrut X., Bibollet-Ruche F., Mpoudi-Ngole E., Bourgeois A., Delaporte E., Peeters M. 2001; Characterization of a novel simian immunodeficiency virus from guereza colobus monkeys ( Colobus guereza ) in Cameroon: a new lineage in the nonhuman primate lentivirus family. J Virol 75:857–866
    [Google Scholar]
  3. Courgnaud V., Salemi M., Pourrut X. 8 other authors 2002; Characterization of a novel simian immunodeficiency virus with a vpu gene from greater spot-nosed monkeys ( Cercopithecus nictitans ) provides new insights into simian/human immunodeficiency virus phylogeny. J Virol 76:8298–8309
    [Google Scholar]
  4. Courgnaud V., Formenty P., Akoua-Koffi C., Noe R., Boesch C., Delaporte E., Peeters M. 2003; Partial molecular characterization of two simian immunodeficiency viruses (SIV) from African colobids: SIVwrc from Western red colobus ( Piliocolobus badius ) and SIVolc from olive colobus ( Procolobus verus ). J Virol 77:744–748
    [Google Scholar]
  5. Gao F., Yue L., White A. T. 7 other authors 1992; Human infection by genetically diverse SIVSM-related HIV-2 in west Africa. Nature 358:495–499
    [Google Scholar]
  6. Gao F., Bailes E., Robertson D. L. 9 other authors 1999; Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes . Nature 397:436–441
    [Google Scholar]
  7. Georges-Courbot M. C., Lu C. Y., Makuwa M. 9 other authors 1998; Natural infection of a household pet red-capped mangabey ( Cercocebus torquatus torquatus ) with a new simian immunodeficiency virus. J Virol 72:600–608
    [Google Scholar]
  8. Hahn B. H., Shaw G. M., De Cock K. M., Sharp P. M. 2000; AIDS as a zoonosis: scientific and public health implications. Science 287:607–614
    [Google Scholar]
  9. Hu J., Switzer W. M., Foley B. T., Robertson D. L., Goeken R. M., Korber B. T., Hirsch V. M., Beer B. E. 2003; Characterization and comparison of recombinant simian immunodeficiency virus from drill ( Mandrillus leucophaeus ) and mandrill ( Mandrillus sphinx ) isolates. J Virol 77:4867–4880
    [Google Scholar]
  10. Korber B., Muldoon M., Theiler J., Gao F., Gupta R., Lapedes A., Hahn B. H., Wolinsky S., Bhattacharya T. 2000; Timing the ancestor of the HIV-1 pandemic strains. Science 288:1789–1796
    [Google Scholar]
  11. Miura T., Sakuragi J., Kawamura M. other authors 1990; Establishment of a phylogenetic survey system for AIDS-related lentiviruses and demonstration of a new HIV-2 subgroup. AIDS 4:1257–1261
    [Google Scholar]
  12. Peeters M., Honore C., Huet T., Bedjabaga L., Ossari S., Bussi P., Cooper R. W., Delaporte E. 1989; Isolation and partial characterization of an HIV-related virus occurring naturally in chimpanzees in Gabon. AIDS 3:625–630
    [Google Scholar]
  13. Peeters M., Courgnaud V., Abela B. 11 other authors 2002; Risk to human health from a plethora of simian immunodeficiency viruses in primate bushmeat. Emerg Infect Dis 8:451–457
    [Google Scholar]
  14. Rambaut A. 2002 SE-AL Sequence Alignment Editor, v2.0a11 University of Oxford; Oxford, UK:
    [Google Scholar]
  15. Santiago M. L., Lukasik M., Kamenya S. 20 other authors 2003; Foci of endemic simian immunodeficiency virus infection in wild-living eastern chimpanzees ( Pan troglodytes schweinfurthii ). J Virol 77:7545–7562
    [Google Scholar]
  16. Souquiere S., Bibollet-Ruche F., Robertson D. L. 17 other authors 2001; Wild Mandrillus sphinx are carriers of two types of lentivirus. J Virol 75:7086–7096
    [Google Scholar]
  17. Swofford D. L. 2002 paup*: Phylogenetic Analysis Using Parsimony (*and Other Methods), version 4·0b10 Sinauer Associates; Sunderland, MA, USA:
    [Google Scholar]
  18. Warren K. S., Niphuis H., Heriyanto Verschoor., J E, Swan R. A., Heeney J. L. 1998; Seroprevalence of specific viral infections in confiscated orangutans ( Pongo pygmaeus ). J Med Primatol 27:33–37
    [Google Scholar]
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