@article{mbs:/content/journal/jgv/10.1099/vir.0.19381-0, author = "Denesvre, Caroline and Soubieux, Denis and Pin, Gaelle and Hue, Dominique and Dambrine, Ginette", title = "Interference between avian endogenous ev/J 4.1 and exogenous ALV-J retroviral envelopes", journal= "Journal of General Virology", year = "2003", volume = "84", number = "12", pages = "3233-3238", doi = "https://doi.org/10.1099/vir.0.19381-0", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.19381-0", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", abstract = "A new family of avian retroviral endogenous sequences designated ev/J or EAV-HP has been identified recently. Here an additional avian ev/J 4.1 endogenous sequence, ev/J 4.1 Rb, is reported. ev/J 4.1 Rb has the most extensive amino acid identity ever described for an endogenous envelope protein with the ALV-J avian leukosis virus. Here, we also demonstrate that ev/J 4.1 Rb functionally pseudotypes murine leukaemia virions and leads to a complete reciprocal interference with ALV-J envelopes. This is the first demonstration of such a high level of envelope interference between endogenous and exogenous avian retroviruses. Our results provide additional clues on the co-evolution of retroviral sequences among vertebrates.", }