1887

Abstract

Group A rotaviruses (RVAs) are enteric pathogens with well-documented zoonotic transmissions to humans. The segmented genome of the virus enables reassortment events which might alter host susceptibility and/or disease course. Genetic analysis of rotavirus in dogs has so far only revealed RVAs with the VP7 and VP4 genome constellation G3P[3]. RVA G3P[3] have also been found in cats, humans, monkeys and bats. In the present study, we described an unusual RVA of genotype G8P[1] which was isolated from an asymptomatically infected young dog. The dog did not show signs of diarrhoea. Analysis of full-length segments of VP2, VP6 and VP7 as well as NSP1–NSP5 revealed a typical bovine-like genotype constellation G8–P[1]–I2–Rx–C2–Mx–A3–N2–T6–E2–H3. Phylogenetic analysis supported the hypothesis of an interspecies transmission from a bovine/artiodactyl species or from humans to the young dog. The isolate was likely to represent a multiple reassortant virus.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/vir.0.069120-0
2015-01-01
2024-04-24
Loading full text...

Full text loading...

/deliver/fulltext/jgv/96/1/106.html?itemId=/content/journal/jgv/10.1099/vir.0.069120-0&mimeType=html&fmt=ahah

References

  1. Dagenais L., Schwers A., Lansival B., Pastoret P.-P. 1980; Searching antibodies directed against bovine rotavirus in sera of dogs, cats and horses in Belgium. Ann Med Vet 124:423–428 (in French)
    [Google Scholar]
  2. De Grazia S., Martella V., Giammanco G. M., Gòmara M. I., Ramirez S., Cascio A., Colomba C., Arista S. 2007; Canine-origin G3P[3] rotavirus strain in child with acute gastroenteritis. Emerg Infect Dis 13:1091–1093 [View Article][PubMed]
    [Google Scholar]
  3. Fujii Y., Shimoike T., Takagi H., Murakami K., Todaka-Takai R., Park Y., Katayama K. 2012; Amplification of all 11 RNA segments of group A rotaviruses based on reverse transcription polymerase chain reaction. Microbiol Immunol 56:630–638 [View Article][PubMed]
    [Google Scholar]
  4. Gentsch J. R., Glass R. I., Woods P., Gouvea V., Gorziglia M., Flores J., Das B. K., Bhan M. K. 1992; Identification of group A rotavirus gene 4 types by polymerase chain reaction. J Clin Microbiol 30:1365–1373[PubMed]
    [Google Scholar]
  5. Ghosh S., Kobayashi N. 2011; Whole-genomic analysis of rotavirus strains: current status and future prospects. Future Microbiol 6:1049–1065 [View Article][PubMed]
    [Google Scholar]
  6. Ghosh S., Gatheru Z., Nyangao J., Adachi N., Urushibara N., Kobayashi N. 2011; Full genomic analysis of a G8P[1] rotavirus strain isolated from an asymptomatic infant in Kenya provides evidence for an artiodactyl-to-human interspecies transmission event. J Med Virol 83:367–376 [View Article][PubMed]
    [Google Scholar]
  7. Green C. 2012 Infectious Diseases of the Dog and Cat, 4th edn. St Louis, MO; Elsevier Saunders;
    [Google Scholar]
  8. He B., Yang F., Yang W., Zhang Y., Feng Y., Zhou J., Xie J., Feng Y., Bao X.other authors 2013; Characterization of a novel G3P[3] rotavirus isolated from a lesser horseshoe bat: a distant relative of feline/canine rotaviruses. J Virol 87:12357–12366 [View Article][PubMed]
    [Google Scholar]
  9. Honma S., Chizhikov V., Santos N., Tatsumi M., do Carmo S. T. Timenetsky M., Linhares A. C., Mascarenhas J. D., Ushijima H., Armah G. E.other authors 2007; Development and validation of DNA microarray for genotyping group A rotavirus VP4 (P[4], P[6], P[8], P[9], and P[14]) and VP7 (G1 to G6, G8 to G10, and G12) genes. J Clin Microbiol 45:2641–2648 [View Article][PubMed]
    [Google Scholar]
  10. Isegawa Y., Nakagomi O., Nakagomi T., Ishida S., Uesugi S., Ueda S. 1993; Determination of bovine rotavirus G and P serotypes by polymerase chain reaction. Mol Cell Probes 7:277–284 [View Article][PubMed]
    [Google Scholar]
  11. Kumar S., Tamura K., Nei M. 2004; MEGA3: integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. Brief Bioinform 5:150–163 [View Article][PubMed]
    [Google Scholar]
  12. Luchs A., Cilli A., Morillo S. G., Carmona R. C., Timenetsky M. C. 2012; Rare G3P[3] rotavirus strain detected in Brazil: possible human–canine interspecies transmission. J Clin Virol 54:89–92 [View Article][PubMed]
    [Google Scholar]
  13. Maes P., Matthijnssens J., Rahman M., Van Ranst M. 2009; RotaC: a web-based tool for the complete genome classification of group A rotaviruses. BMC Microbiol 9:238 [View Article][PubMed]
    [Google Scholar]
  14. Maniatis T., Fritsch E. F., Sambrook J. 1982 Molecular Cloning, A Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory;
    [Google Scholar]
  15. Martella V., Bányai K., Matthijnssens J., Buonavoglia C., Ciarlet M. 2010; Zoonotic aspects of rotaviruses. Vet Microbiol 140:246–255 [View Article][PubMed]
    [Google Scholar]
  16. Matthijnssens J., Van Ranst M. 2012; Genotype constellation and evolution of group A rotaviruses infecting humans. Curr Opin Virol 2:426–433 [View Article][PubMed]
    [Google Scholar]
  17. Matthijnssens J., Ciarlet M., Heiman E., Arijs I., Delbeke T., McDonald S. M., Palombo E. A., Iturriza-Gómara M., Maes P.other authors 2008a; Full genome-based classification of rotaviruses reveals a common origin between human Wa-Like and porcine rotavirus strains and human DS-1-like and bovine rotavirus strains. J Virol 82:3204–3219 [View Article][PubMed]
    [Google Scholar]
  18. Matthijnssens J., Ciarlet M., Rahman M., Attoui H., Bányai K., Estes M. K., Gentsch J. R., Iturriza-Gómara M., Kirkwood C. D.other authors 2008b; Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segments. Arch Virol 153:1621–1629 [View Article][PubMed]
    [Google Scholar]
  19. Matthijnssens J., De Grazia S., Piessens J., Heylen E., Zeller M., Giammanco G. M., Bányai K., Buonavoglia C., Ciarlet M.other authors 2011; Multiple reassortment and interspecies transmission events contribute to the diversity of feline, canine and feline/canine-like human group A rotavirus strains. Infect Genet Evol 11:1396–1406 [View Article][PubMed]
    [Google Scholar]
  20. Maunula L., Von Bonsdorff C. H. 2002; Frequent reassortments may explain the genetic heterogeneity of rotaviruses: analysis of Finnish rotavirus strains. J Virol 76:11793–11800 [View Article][PubMed]
    [Google Scholar]
  21. McNulty M. S., Allan G. M., Thompson D. J., O’Boyle J. D. 1978; Antibody to rotavirus in dogs and cats. Vet Rec 102:534–535 [View Article][PubMed]
    [Google Scholar]
  22. Oldenburg U., Danner K., Krauss H. 1984; [Significance of rotavirus infections in dogs]. Zentralbl Veterinarmed B 31:297–302 (in German) [View Article][PubMed]
    [Google Scholar]
  23. Papp H., László B., Jakab F., Ganesh B., De Grazia S., Matthijnssens J., Ciarlet M., Martella V., Bányai K. 2013; Review of group A rotavirus strains reported in swine and cattle. Vet Microbiol 165:190–199 [View Article][PubMed]
    [Google Scholar]
  24. Park S. I., Matthijnssens J., Saif L. J., Kim H. J., Park J. G., Alfajaro M. M., Kim D. S., Son K. Y., Yang D. K.other authors 2011; Reassortment among bovine, porcine and human rotavirus strains results in G8P[7] and G6P[7] strains isolated from cattle in South Korea. Vet Microbiol 152:55–66 [View Article][PubMed]
    [Google Scholar]
  25. Tate J. E., Burton A. H., Boschi-Pinto C., Steele A. D., Duque J., Parashar U. D.WHO-coordinated Global Rotavirus Surveillance Network 2012; 2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis. Lancet Infect Dis 12:136–141 [View Article][PubMed]
    [Google Scholar]
  26. Tsugawa T., Hoshino Y. 2008; Whole genome sequence and phylogenetic analyses reveal human rotavirus G3P[3] strains Ro1845 and HCR3A are examples of direct virion transmission of canine/feline rotaviruses to humans. Virology 380:344–353 [View Article][PubMed]
    [Google Scholar]
  27. Wang Y. H., Pang B. B., Zhou X., Ghosh S., Tang W. F., Peng J. S., Hu Q., Zhou D. J., Kobayashi N. 2013; Complex evolutionary patterns of two rare human G3P[9] rotavirus strains possessing a feline/canine-like H6 genotype on an AU-1-like genotype constellation. Infect Genet Evol 16:103–112 [View Article][PubMed]
    [Google Scholar]
  28. Westerman L. E., Jiang B., McClure H. M., Snipes-Magaldi L. J., Griffin D. D., Shin G., Gentsch J. R., Glass R. I. 2006; Isolation and characterization of a new simian rotavirus, YK-1. Virol J 3:40 [View Article][PubMed]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/vir.0.069120-0
Loading
/content/journal/jgv/10.1099/vir.0.069120-0
Loading

Data & Media loading...

Supplements

Supplementary Data

PDF
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error