1887

Abstract

The strain JS11C1, a member of a putative new subgroup of avian leukosis virus (ALV) that is different from all six known subgroups from chickens based on Gp85 amino acid sequence comparison, was isolated from Chinese native chicken breeds in 2012. In order to further study the genome structure, biological characteristics, and the evolutionary relationship of the virus with others of known subgroups from infected chickens, we determined the complete genome sequence, constructed an infectious clone of ALV strain JS11C1, and performed comparative analysis using the whole genome sequence or elements with that of other ALVs available in GenBank. The results showed that the full-length sequence of the JS11C1 DNA provirus genome was 7707 bp, which is consistent with a genetic organization typical of a replication-competent type C retrovirus lacking viral oncogenes. The rescued infectious clone of JS11C1 showed similar growth rate and biological characteristics to its original virus. All the comparison analyses based on whole genomes support the opinion that the new isolates are relatively distantly related to any known subgroups of ALVs and might be classified as a new subgroup.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/vir.0.067264-0
2014-11-01
2019-11-22
Loading full text...

Full text loading...

/deliver/fulltext/jgv/95/11/2512.html?itemId=/content/journal/jgv/10.1099/vir.0.067264-0&mimeType=html&fmt=ahah

References

  1. Calnek B. W.. ( 1968;). Lymphoid leukosis virus: a survey of commercial breeding flocks for genetic resistance and incidence of embryo infection. . Avian Dis 12:, 104–111. [CrossRef][PubMed]
    [Google Scholar]
  2. Chang S. W., Hsu M. F., Wang C. H.. ( 2013;). Gene detection, virus isolation, and sequence analysis of avian leukosis viruses in Taiwan country chickens. . Avian Dis 57:, 172–177. [CrossRef][PubMed]
    [Google Scholar]
  3. Cui Z. Z., Du Y., Zhang Z., Silva R. F.. ( 2003;). Comparison of Chinese field strains of avian leukosis subgroup J viruses with prototype strain HPRS-103 and United States strains. . Avian Dis 47:, 1321–1330. [CrossRef][PubMed]
    [Google Scholar]
  4. Du Y., Cui Z. Z., Qin A., Silva R. F., Lee L. F.. ( 2000;). Isolation of subgroup J avian leukosis viruses and their partial sequence comparison. . Bing Du Xue Bao 16:, 341–346 (in Chinese).
    [Google Scholar]
  5. Hatai H., Ochiai K., Tomioka Y., Toyoda T., Hayashi K., Anada M., Kato M., Toda A., Ohashi K.. & other authors ( 2005;). Nested polymerase chain reaction for detection of the avian leukosis virus causing so-called fowl glioma. . Avian Pathol 34:, 473–479. [CrossRef][PubMed]
    [Google Scholar]
  6. Hatai H., Ochiai K., Murakami M., Imanishi S., Tomioka Y., Toyoda T., Ohashi K., Umemura T.. ( 2008a;). Prevalence of fowl glioma-inducing virus in chickens of zoological gardens in Japan and nucleotide variation in the env gene. . J Vet Med Sci 70:, 469–474. [CrossRef][PubMed]
    [Google Scholar]
  7. Hatai H., Ochiai K., Nagakura K., Imanishi S., Ochi A., Kozakura R., Ono M., Goryo M., Ohashi K., Umemura T.. ( 2008b;). A recombinant avian leukosis virus associated with fowl glioma in layer chickens in Japan. . Avian Pathol 37:, 127–137. [CrossRef][PubMed]
    [Google Scholar]
  8. Iwata N., Ochiai K., Hayashi K., Ohashi K., Umemura T.. ( 2002;). Avian retrovirus infection causes naturally occurring glioma: isolation and transmission of a virus from so-called fowl glioma. . Avian Pathol 31:, 193–199. [CrossRef][PubMed]
    [Google Scholar]
  9. Jackson C.. ( 1948;). Relationship of glioma to encephalitis in the domestic fowl, and an associated parasitic agent. . Nature 161:, 441–442. [CrossRef][PubMed]
    [Google Scholar]
  10. Maas R., van Zoelen D., Oei H., Claassen I.. ( 2006;). Replacement of primary chicken embryonic fibroblasts (CEF) by the DF-1 cell line for detection of avian leucosis viruses. . Biologicals 34:, 177–181. [CrossRef][PubMed]
    [Google Scholar]
  11. Miwa T., Kedes L.. ( 1987;). Duplicated CArG box domains have positive and mutually dependent regulatory roles in expression of the human alpha-cardiac actin gene. . Mol Cell Biol 7:, 2803–2813.[PubMed]
    [Google Scholar]
  12. Mohun T. J., Taylor M. V., Garrett N., Gurdon J. B.. ( 1989;). The CArG promoter sequence is necessary for muscle-specific transcription of the cardiac actin gene in Xenopus embryos. . EMBO J 8:, 1153–1161.[PubMed]
    [Google Scholar]
  13. Morgan H. R.. ( 1973;). Avian leukosis-sarcoma virus antibodies in wildfowl, domestic chickens and man in Kenya. . Proc Soc Exp Biol Med 144:, 1–4. [CrossRef][PubMed]
    [Google Scholar]
  14. Ochi A., Ochiai K., Kobara A., Nakamura S., Hatai H., Handharyani E., Tiemann I., Tanaka I. B. III, Toyoda T.. & other authors ( 2012;). Epidemiological study of fowl glioma-inducing virus in chickens in Asia and Germany. . Avian Pathol 41:, 299–309. [CrossRef][PubMed]
    [Google Scholar]
  15. Ochiai K., Ohashi K., Mukai T., Kimura T., Umemura T., Itakura C.. ( 1999;). Evidence of neoplastic nature and viral aetiology of so-called fowl glioma. . Vet Rec 145:, 79–81. [CrossRef][PubMed]
    [Google Scholar]
  16. Okazaki W., Purchase H. G., Crittenden L. B.. ( 1982;). Pathogenicity of avian leukosis viruses. . Avian Dis 26:, 553–559. [CrossRef][PubMed]
    [Google Scholar]
  17. Payne L. N.. ( 1992b;). Biology of avian retroviruses. . In The Retroviridae, vol. 1, pp. 299–404. Edited by Levy J. A... New York:: Plenum Press;. [CrossRef]
    [Google Scholar]
  18. Payne L. N., Fadly A. M.. ( 1997;). Leukosis/sarcoma group. . In Diseases of Poultry, , 10th edn., pp. 414–466. Edited by Calnek B. W., Barnes H. J., Beard C. W., McDougald L. R., Saif Y. M.. Ames, IA:: Iowa state University Press;. [CrossRef]
    [Google Scholar]
  19. Ruddell A., Linial M. L., Groudine M.. ( 1989;). Tissue-specific lability and expression of avian leukosis virus long terminal repeat enhancer-binding proteins. . Mol Cell Biol 9:, 5660–5668. [CrossRef][PubMed]
    [Google Scholar]
  20. Payne L. N., Brown S. R., Bumstead N., Howes K., Frazier J. A., Thouless M. E.. ( 1991;). A novel subgroup of exogenous avian leukosis virus in chickens. . J Gen Virol 72:, 801–807. [CrossRef][PubMed]
    [Google Scholar]
  21. Payne L. N., Howes K., Gillespie A. M., Smith L. M.. ( 1992a;). Host range of Rous sarcoma virus pseudotype RSV(HPRS-103) in 12 avian species: support for a new avian retrovirus envelope subgroup, designated J. . J Gen Virol 73:, 2995–2997. [CrossRef][PubMed]
    [Google Scholar]
  22. Ross H. L., Gartner S., McArthur J. C., Corboy J. R., McAllister J. J., Millhouse S., Wigdahl B.. ( 2001;). HIV-1 LTR C/EBP binding site sequence configurations preferentially encountered in brain lead to enhanced C/EBP factor binding and increased LTR-specific activity. . J Neurovirol 7:, 235–249. [CrossRef][PubMed]
    [Google Scholar]
  23. Ruddell A.. ( 1995;). Transcription regulatory elements of the avian retroviral long terminal repeat. . Virology 206:, 1–7. [CrossRef][PubMed]
    [Google Scholar]
  24. Sandelin K., Estola T.. ( 1974;). Occurrence of different subgroups of avian leukosis virus in Finnish poultry. . Avian Pathol 3:, 159–168. [CrossRef][PubMed]
    [Google Scholar]
  25. Smith E. J.. ( 1987;). Endogenous avian leukemia viruses. . In Avian Leukosis, pp. 101–120. Edited by De Boer G. F... Boston:: Martinus Nijhoff;.
    [Google Scholar]
  26. Somes R. G. Jr. ( 1998;). International registry of poultry genetic stocks. . Storrs Agricultural Experiment Station. Paper 29.
    [Google Scholar]
  27. Summers B. A., Cummings J. F., de Lahunta A.. ( 1995;). Tumors of the central nervous system. . In Veterinary Neuropathology, pp. 351–401. Edited by Summers B.A., Cummings J.F., de Lahunta A... St. Louis, MO:: Mosby;.
    [Google Scholar]
  28. Tomioka Y., Ochiai K., Ohashi K., Kimura T., Umemura T.. ( 2003;). In ovo infection with an avian leukosis virus causing fowl glioma: viral distribution and pathogenesis. . Avian Pathol 32:, 617–624. [CrossRef][PubMed]
    [Google Scholar]
  29. Tomioka Y., Ochiai K., Ohashi K., Ono E., Toyoda T., Kimura T., Umemura T.. ( 2004;). Genome sequence analysis of the avian retrovirus causing so-called fowl glioma and the promoter activity of the long terminal repeat. . J Gen Virol 85:, 647–652. [CrossRef][PubMed]
    [Google Scholar]
  30. Wang X., Zhao P., Cui Z. Z.. ( 2012;). [Identification of a new subgroup of avian leukosis virus isolated from Chinese indigenous chicken breeds]. . Bing Du Xue Bao 28:, 609–614 (in Chinese, with English abstract).[PubMed]
    [Google Scholar]
  31. Zachow K. R., Conklin K. F.. ( 1992;). CArG, CCAAT, and CCAAT-like protein binding sites in avian retrovirus long terminal repeat enhancers. . J Virol 66:, 1959–1970.[PubMed]
    [Google Scholar]
  32. Zhang Q. C., Zhao D. M., Guo H. J., Cui Z. Z.. ( 2010;). [Isolation and identification of a subgroup A avian leukosis virus from imported meat-type grand-parent chickens]. . Virol Sin 25:, 130–136 (in Chinese, with English abstract). [CrossRef][PubMed]
    [Google Scholar]
  33. Zhao D. M., Zhang Q. C., Cui Z. Z.. ( 2010;). [Isolation and identification of a subgroup B avian leukosis virus from chickens of Chinese native breed Luhua]. . Bing Du Xue Bao 26:, 53–57 (in Chinese, with English abstract).[PubMed]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/vir.0.067264-0
Loading
/content/journal/jgv/10.1099/vir.0.067264-0
Loading

Data & Media loading...

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error