Skip to content
1887

Journal of General Virology header logo Journal of General Virology

Volume 94, Issue 5

Isolation and DNA characterization of a simian retrovirus 5 from a Japanese monkey () No Access

Abstract

An SRV-like virus was isolated from a colony-born Japanese monkey. To identify this SRV-like virus, we designed universal primers at regions that were conserved among the reported SRV sequences in the 5′-LTR and the short ORF and we obtained plasmid clones containing the complete , , and genes. The full-length sequences of the isolate were determined from the plasmids and by direct sequencing. Sequence comparisons and phylogenetic analyses indicated that this SRV-like virus had a sequence identical to the reported 626 bp of SRV-5. In this study, we isolated SRV5/JPN/2005/V1 from a Japanese monkey and characterized the full-length SRV-5 sequence.

  • Received:
  • Accepted:
  • Published Online:
© 2013 SGM
Loading

Article metrics loading...

/content/journal/jgv/10.1099/vir.0.047621-0
2013-05-01
2025-04-22
Loading full text...

Full text loading...

References

  1. Bryant M. L., Marx P. A., Shiigi S. M., Wilson B. J., McNulty W. P., Gardner M. B. 1986; Distribution of type D retrovirus sequences in tissues of macaques with simian acquired immune deficiency and retroperitoneal fibromatosis. Virology 150:149–160 [View Article][PubMed]
     [Google Scholar]
  2. Daniel M. D., King N. W., Letvin N. L., Hunt R. D., Sehgal P. K., Desrosiers R. C. 1984; A new type D retrovirus isolated from macaques with an immunodeficiency syndrome. Science 223:602–605 [View Article][PubMed]
     [Google Scholar]
  3. Fujimoto K., Takano J., Narita T., Hanari K., Shimozawa N., Sankai T., Yosida T., Terao K., Kurata T., Yasutomi Y. 2010; Simian betaretrovirus infection in a colony of cynomolgus monkeys (Macaca fascicularis). Comp Med 60:51–53[PubMed]
     [Google Scholar]
  4. Giddens W. E. Jr, Tsai C. C., Morton W. R., Ochs H. D., Knitter G. H., Blakley G. A. 1985; Retroperitoneal fibromatosis and acquired immunodeficiency syndrome in macaques. Pathologic observations and transmission studies. Am J Pathol 119:253–263[PubMed]
     [Google Scholar]
  5. Grant R. F., Malinak C. J., Wu H., Sabo A., Tsai C. C. 1995; PCR amplification and DNA sequencing of SRV-2 from archived tumor tissues. Virus Res 36:187–200 [View Article][PubMed]
     [Google Scholar]
  6. Hara M., Sata T., Kikuchi T., Nakajima N., Uda A., Fujimoto K., Baba T., Mukai R. 2005; Isolation and characterization of a new simian retrovirus type D subtype from monkeys at the Tsukuba Primate Center, Japan. Microbes Infect 7:126–131 [View Article][PubMed]
     [Google Scholar]
  7. Hefti E., Ip J., Giddens W. E. Jr, Panem S. 1983; Isolation of a unique retrovirus, MNV-1, from Macaca nemestrina. Virology 127:309–319 [View Article][PubMed]
     [Google Scholar]
  8. Larkin M. A., Blackshields G., Brown N. P., Chenna R., McGettigan P. A., McWilliam H., Valentin F., Wallace I. M., Wilm A.other authors 2007; clustal w and clustal_x version 2.0. Bioinformatics 23:2947–2948 [View Article][PubMed]
     [Google Scholar]
  9. Lerche N. W., Marx P. A., Osborn K. G., Maul D. H., Lowenstine L. J., Bleviss M. L., Moody P., Henrickson R. V., Gardner M. B. 1987; Natural history of endemic type D retrovirus infection and acquired immune deficiency syndrome in group-housed rhesus monkeys. J Natl Cancer Inst 79:847–854[PubMed]
     [Google Scholar]
  10. Lerche N. W., Switzer W. M., Yee J. L., Shanmugam V., Rosenthal A. N., Chapman L. E., Folks T. M., Heneine W. 2001; Evidence of infection with simian type D retrovirus in persons occupationally exposed to nonhuman primates. J Virol 75:1783–1789 [View Article][PubMed]
     [Google Scholar]
  11. Li B., Axthelm M. K., Machida C. A. 2000; Simian retrovirus serogroup 5: partial gag-prt sequence and viral RNA distribution in an infected rhesus macaque. Virus Genes 21:241–248 [View Article][PubMed]
     [Google Scholar]
  12. Liska V., Lerche N. W., Ruprecht R. M. 1997; Simultaneous detection of simian retrovirus type D serotypes 1, 2, and 3 by polymerase chain reaction. AIDS Res Hum Retroviruses 13:433–437 [View Article][PubMed]
     [Google Scholar]
  13. Marracci G. H., Kelley R. D., Pilcher K. Y., Crabtree L., Shiigi S. M., Avery N., Leo G., Webb M. C., Hallick L. M.other authors 1995; Simian AIDS type D serogroup 2 retrovirus: isolation of an infectious molecular clone and sequence analyses of its envelope glycoprotein gene and 3′ long terminal repeat. J Virol 69:2621–2628[PubMed]
     [Google Scholar]
  14. Marracci G. H., Avery N. A., Shiigi S. M., Couch G., Palmer H., Pilcher K. Y., Nichols H., Hallick L. M., Axthelm M. K., Machida C. A. 1999; Molecular cloning and cell-specific growth characterization of polymorphic variants of type D serogroup 2 simian retroviruses. Virology 261:43–58 [View Article][PubMed]
     [Google Scholar]
  15. Marx P. A., Maul D. H., Osborn K. G., Lerche N. W., Moody P., Lowenstine L. J., Henrickson R. V., Arthur L. O., Gilden R. V.other authors 1984; Simian AIDS: isolation of a type D retrovirus and transmission of the disease. Science 223:1083–1086 [View Article][PubMed]
     [Google Scholar]
  16. Nandi J. S., Bhavalkar-Potdar V., Tikute S., Raut C. G. 2000; A novel type D simian retrovirus naturally infecting the Indian Hanuman langur (Semnopithecus entellus). Virology 277:6–13 [View Article][PubMed]
     [Google Scholar]
  17. Nandi J. S., Van Dooren S., Chhangani A. K., Mohnot S. M. 2006; New simian beta retroviruses from rhesus monkeys (Macaca mulatta) and langurs (Semnopithecus entellus) from Rajasthan, India. Virus Genes 33:107–116 [View Article][PubMed]
     [Google Scholar]
  18. Philipp-Staheli J., Marquardt T., Thouless M. E., Bruce A. G., Grant R. F., Tsai C. C., Rose T. M. 2006; Genetic variability of the envelope gene of type D simian retrovirus-2 (SRV-2) subtypes associated with SAIDS-related retroperitoneal fibromatosis in different macaque species. Virol J 3:11 [View Article][PubMed]
     [Google Scholar]
  19. Power M. D., Marx P. A., Bryant M. L., Gardner M. B., Barr P. J., Luciw P. A. 1986; Nucleotide sequence of SRV-1, a type D simian acquired immune deficiency syndrome retrovirus. Science 231:1567–1572 [View Article][PubMed]
     [Google Scholar]
  20. Saitou N., Nei M. 1987; The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 4:406–425[PubMed]
     [Google Scholar]
  21. Sonigo P., Barker C., Hunter E., Wain-Hobson S. 1986; Nucleotide sequence of Mason-Pfizer monkey virus: an immunosuppressive D-type retrovirus. Cell 45:375–385 [View Article][PubMed]
     [Google Scholar]
  22. Stromberg K., Benveniste R. E., Arthur L. O., Rabin H., Giddens W. E. Jr, Ochs H. D., Morton W. R., Tsai C. C. 1984; Characterization of exogenous type D retrovirus from a fibroma of a macaque with simian AIDS and fibromatosis. Science 224:289–2 [View Article][PubMed]
     [Google Scholar]
  23. Tamura K., Dudley J., Nei M., Kumar S. 2007; mega4: Molecular Evolutionary Genetics Analysis (mega) software version 4.0. Mol Biol Evol 24:1596–1599 [View Article][PubMed]
     [Google Scholar]
  24. Thayer R. M., Power M. D., Bryant M. L., Gardner M. B., Barr P. J., Luciw P. A. 1987; Sequence relationships of type D retroviruses which cause simian acquired immunodeficiency syndrome. Virology 157:317–329 [View Article][PubMed]
     [Google Scholar]
  25. Wang Y., Thouless M. E. 1996; Use of polymerase chain reaction for diagnosis of type D simian retrovirus infection in macaque blood. Lab Anim Sci 46:187–192[PubMed]
     [Google Scholar]
  26. White J. A., Todd P. A., Rosenthal A. N., Yee J. L., Grant R., Lerche N. W. 2009; Development of a generic real-time PCR assay for simultaneous detection of proviral DNA of simian betaretrovirus serotypes 1, 2, 3, 4 and 5 and secondary uniplex assays for specific serotype identification. J Virol Methods 162:148–154 [View Article][PubMed]
     [Google Scholar]
  27. Zao C. L., Armstrong K., Tomanek L., Cooke A., Berger R., Estep J. S., Marx P. A., Trask J. S., Smith D. G.other authors 2010; The complete genome and genetic characteristics of SRV-4 isolated from cynomolgus monkeys (Macaca fascicularis). Virology 405:390–396 [View Article][PubMed]
     [Google Scholar]
/content/journal/jgv/10.1099/vir.0.047621-0
Loading
Isolation and DNA characterization of a simian retrovirus 5 from a Japanese monkey (Macaca fuscata)
J. Gen. Virol. 94, 955 (2013); https://doi.org/10.1099/vir.0.047621-0
/content/journal/jgv/10.1099/vir.0.047621-0
/content/journal/jgv/10.1099/vir.0.047621-0
Loading

Data & Media loading...

Supplements

Supplementary material 1

PDF

Most cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error