1887

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Volume 93, Issue 6

A third gyrovirus species in human faeces Free

Abstract

Until 2011 the genus in the family consisted of a single virus (Chicken anemia virus or CAV) causing a common immunosuppressive disease in chickens when a second gyrovirus (HGyV) was reported on the skin of 4 % of healthy humans. HGyV is very closely related to a recently described chicken gyrovirus, AGV2, suggesting that they belong to the same viral species. During a viral metagenomic analysis of 100 human faeces from children with diarrhoea in Chile we identified multiple known human pathogens (adenoviruses, enteroviruses, astroviruses, sapoviruses, noroviruses, parechoviruses and rotaviruses) and a novel gyrovirus species we named GyV3 sharing <63 % similarity with other gyrovirus proteins with evidence of recombination with CAV in its UTR. consensus PCR revealed a high prevalence of CAV DNA in diarrhoea and normal faeces from Chilean children and faeces of USA cats and dogs, which may reflect consumption of CAV-infected/vaccinated chickens. Whether GyV3 can infect humans and/or chickens requires further studies.

  • Received:
  • Accepted:
  • Published Online:
© 2012 SGM
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2012-06-01
2023-09-28
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A third gyrovirus species in human faeces
J. Gen. Virol. 93, 1356 (2012); https://doi.org/10.1099/vir.0.041731-0
/content/journal/jgv/10.1099/vir.0.041731-0
/content/journal/jgv/10.1099/vir.0.041731-0
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