1887

Abstract

Procedures for discriminating scrapie from bovine spongiform encephalopathy (BSE) in sheep are relevant to ascertain whether BSE has entered the sheep population. This study was aimed at investigating whether the suitability of an official EU discriminative method is affected by the sheep PrP genotype and route of infection.

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2012-02-01
2020-07-11
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References

  1. Baron T. G., Madec J. Y., Calavas D., Richard Y., Barillet F.. 2000; Comparison of French natural scrapie isolates with bovine spongiform encephalopathy and experimental scrapie infected sheep. Neurosci Lett284:175–178 [CrossRef][PubMed]
    [Google Scholar]
  2. Bellworthy S. J., Dexter G., Stack M., Chaplin M., Hawkins S. A., Simmons M. M., Jeffrey M., Martin S., Gonzalez L., Hill P.. 2005; Natural transmission of BSE between sheep within an experimental flock. Vet Rec157:206[PubMed][CrossRef]
    [Google Scholar]
  3. Bruce M., Chree A., McConnell I., Foster J., Pearson G., Fraser H.. 1994; Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier. Philos Trans R Soc Lond B Biol Sci343:405–411 [CrossRef][PubMed]
    [Google Scholar]
  4. Bruce M. E., Will R. G., Ironside J. W., McConnell I., Drummond D., Suttie A., McCardle L., Chree A., Hope J.. other authors 1997; Transmissions to mice indicate that ‘new variant’ CJD is caused by the BSE agent. Nature389:498–501 [CrossRef][PubMed]
    [Google Scholar]
  5. DNV (Det Norske Veritas) 2001; Assessment of risk due to BSE infectivity from disposal of sheep. UK report for DEFRA, C716124
  6. EFSA 2007; Quantitative risk assessment on the residual BSE risk in sheep meat and meat products. Opinion of the Scientific Panel on Biological Hazards. The EFSA Journal442:1–44
    [Google Scholar]
  7. Foster J. D., Hope J., Fraser H.. 1993; Transmission of bovine spongiform encephalopathy to sheep and goats. Vet Rec133:339–341 [CrossRef][PubMed]
    [Google Scholar]
  8. Foster J. D., Bruce M., McConnell I., Chree A., Fraser H.. 1996; Detection of BSE infectivity in brain and spleen of experimentally infected sheep. Vet Rec138:546–548 [CrossRef][PubMed]
    [Google Scholar]
  9. González L., Martin S., Houston F. E., Hunter N., Reid H. W., Bellworthy S. J., Jeffrey M.. 2005; Phenotype of disease-associated PrP accumulation in the brain of bovine spongiform encephalopathy experimentally infected sheep. J Gen Virol86:827–838 [CrossRef][PubMed]
    [Google Scholar]
  10. González L., Chianini F., Martin S., Sisó S., Gibbard L., Reid H. W., Jeffrey M.. 2007; Comparative titration of experimental ovine BSE infectivity in sheep and mice. J Gen Virol88:714–717 [CrossRef][PubMed]
    [Google Scholar]
  11. Gretzschel A., Buschmann A., Eiden M., Ziegler U., Lühken G., Erhardt G., Groschup M. H.. 2005; Strain typing of German transmissible spongiform encephalopathies field cases in small ruminants by biochemical methods. J Vet Med B Infect Dis Vet Public Health52:55–63 [CrossRef][PubMed]
    [Google Scholar]
  12. Hill A. F., Desbruslais M., Joiner S., Sidle K. C. L., Gowland I., Collinge J., Doey L. J., Lantos P.. 1997; The same prion strain causes vCJD and BSE. Nature389:448–450, 526 [CrossRef][PubMed]
    [Google Scholar]
  13. Hope J., Wood S. C. E. R., Birkett C. R., Chong A., Bruce M. E., Cairns D., Goldmann W., Hunter N., Bostock C. J.. 1999; Molecular analysis of ovine prion protein identifies similarities between BSE and an experimental isolate of natural scrapie, CH1641. J Gen Virol80:1–4[PubMed]
    [Google Scholar]
  14. Houston F., Goldmann W., Chong A., Jeffrey M., González L., Foster J., Parnham D., Hunter N.. 2003; Prion diseases: BSE in sheep bred for resistance to infection. Nature423:498 [CrossRef][PubMed]
    [Google Scholar]
  15. Jeffrey M., Martin S., González L., Ryder S. J., Bellworthy S. J., Jackman R.. 2001; Differential diagnosis of infections with the bovine spongiform encephalopathy (BSE) and scrapie agents in sheep. J Comp Pathol125:271–284 [CrossRef][PubMed]
    [Google Scholar]
  16. Lasmézas C. I., Fournier J. G., Nouvel V., Boe H., Marcé D., Lamoury F., Kopp N., Hauw J. J., Ironside J.. other authors 2001; Adaptation of the bovine spongiform encephalopathy agent to primates and comparison with Creutzfeldt–Jakob disease: implications for human health. Proc Natl Acad Sci U S A98:4142–4147 [CrossRef][PubMed]
    [Google Scholar]
  17. Lezmi S., Martin S., Simon S., Comoy E., Bencsik A., Deslys J. P., Grassi J., Jeffrey M., Baron T.. 2004; Comparative molecular analysis of the abnormal prion protein in field scrapie cases and experimental bovine spongiform encephalopathy in sheep by use of Western blotting and immunohistochemical methods. J Virol78:3654–3662 [CrossRef][PubMed]
    [Google Scholar]
  18. Martin S., González L., Chong A., Houston F. E., Hunter N., Jeffrey M.. 2005; Immunohistochemical characteristics of disease-associated PrP are not altered by host genotype or route of inoculation following infection of sheep with bovine spongiform encephalopathy. J Gen Virol86:839–848 [CrossRef][PubMed]
    [Google Scholar]
  19. Nonno R., Esposito E., Vaccari G., Conte M., Marcon S., Di Bari M., Ligios C., Di Guardo G., Agrimi U.. 2003; Molecular analysis of cases of Italian sheep scrapie and comparison with cases of bovine spongiform encephalopathy (BSE) and experimental BSE in sheep. J Clin Microbiol41:4127–4133 [CrossRef][PubMed]
    [Google Scholar]
  20. Padilla D., Béringue V., Espinosa J. C., Andreoletti O., Jaumain E., Reine F., Herzog L., Gutierrez-Adan A., Pintado B.. other authors 2011; Sheep and goat BSE propagate more efficiently than cattle BSE in human PrP transgenic mice. PLoS Pathog7:e1001319 [CrossRef][PubMed]
    [Google Scholar]
  21. Pirisinu L., Migliore S., Di Bari M. A., Esposito E., Baron T., D’Agostino C., De Grossi L., Vaccari G., Agrimi U., Nonno R.. 2011; Molecular discrimination of sheep bovine spongiform encephalopathy from scrapie. Emerg Infect Dis17:695–698[PubMed][CrossRef]
    [Google Scholar]
  22. Plinston C., Hart P., Chong A., Hunter N., Foster J., Piccardo P., Manson J. C., Barron R. M.. 2011; Increased susceptibility of human-PrP transgenic mice to bovine spongiform encephalopathy infection following passage in sheep. J Virol85:1174–1181 [CrossRef][PubMed]
    [Google Scholar]
  23. Ronzon F., Bencsik A., Lezmi S., Vulin J., Kodjo A., Baron T.. 2006; BSE inoculation to prion diseases-resistant sheep reveals tricky silent carriers. Biochem Biophys Res Commun350:872–877 [CrossRef][PubMed]
    [Google Scholar]
  24. Simon S., Nugier J., Morel N., Boutal H., Créminon C., Benestad S. L., Andréoletti O., Lantier F., Bilheude J. M.. other authors 2008; Rapid typing of transmissible spongiform encephalopathy strains with differential ELISA. Emerg Infect Dis14:608–616 [CrossRef][PubMed]
    [Google Scholar]
  25. Stack M. J., Chaplin M. J., Clark J.. 2002; Differentiation of prion protein glycoforms from naturally occurring sheep scrapie, sheep-passaged scrapie strains (CH1641 and SSBP1), bovine spongiform encephalopathy (BSE) cases and Romney and Cheviot breed sheep experimentally inoculated with BSE using two monoclonal antibodies. Acta Neuropathol104:279–286[PubMed]
    [Google Scholar]
  26. Stack M., Jeffrey M., Gubbins S., Grimmer S., González L., Martin S., Chaplin M., Webb P., Simmons M.. other authors 2006; Monitoring for bovine spongiform encephalopathy in sheep in Great Britain, 1998–2004. J Gen Virol87:2099–2107 [CrossRef][PubMed]
    [Google Scholar]
  27. Stack M., González L., Jeffrey M., Martin S., Macaldowie C., Chaplin M., Thorne J., Sayers R., Davis L.. other authors 2009; Three serial passages of bovine spongiform encephalopathy in sheep do not significantly affect discriminatory test results. J Gen Virol90:764–768 [CrossRef][PubMed]
    [Google Scholar]
  28. Thuring C. M., Erkens J. H., Jacobs J. G., Bossers A., Van Keulen L. J., Garssen G. J., Van Zijderveld F. G., Ryder S. J., Groschup M. H.. other authors 2004; Discrimination between scrapie and bovine spongiform encephalopathy in sheep by molecular size, immunoreactivity, and glycoprofile of prion protein. J Clin Microbiol42:972–980 [CrossRef][PubMed]
    [Google Scholar]
  29. Vaccari G., D’Agostino C., Nonno R., Rosone F., Conte M., Di Bari M. A., Chiappini B., Esposito E., De Grossi L.. other authors 2007; Prion protein alleles showing a protective effect on the susceptibility of sheep to scrapie and bovine spongiform encephalopathy. J Virol81:7306–7309 [CrossRef][PubMed]
    [Google Scholar]
  30. Vulin J., Biacabe A. G., Cazeau G., Calavas D., Baron T.. 2011; Molecular typing of protease-resistant prion protein in transmissible spongiform encephalopathies of small ruminants, France, 2002-2009. Emerg Infect Dis17:55–63 [CrossRef][PubMed]
    [Google Scholar]
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