1887

Abstract

Astroviruses (AstVs) have been identified only occasionally in dogs. A canine AstV, strain Bari/08/ITA, was detected from a pup with gastroenteric signs and the virus was isolated in cell culture and characterized molecularly. In the full-length capsid protein, the virus displayed genetic similarities (83.5 % aa identity) to another canine AstV strain, although a high rate of variation occurred in the hypervariable domain, which is related to AstV antigenic specificity. Specific antibodies were detected in the convalescent dog, indicating seroconversion, and in 59 % of a collection of dog serum samples. Using primers specific for canine AstV, designed to detect a conserved region of ORF1b, canine AstVs were detected in 24.5 % of young pups with gastroenteritis, either alone or in mixed infections with other canine pathogens. In contrast, AstVs were detected in only 9.3 % of asymptomatic pups. These findings indicate that canine AstVs are common in dogs and may suggest a possible role as canine enteric pathogens.

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2011-08-01
2021-02-25
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References

  1. Appel M. J. 1988; Does canine coronavirus augment the effects of subsequent parvovirus infection?. Vet Med 83:360–366
    [Google Scholar]
  2. Bass D. M., Upadhyayula U. 1997; Characterization of human serotype 1 astrovirus-neutralizing epitopes. J Virol 71:8666–8671[PubMed]
    [Google Scholar]
  3. Blomström A. L., Widén F., Hammer A. S., Belák S., Berg M. 2010; Detection of a novel astrovirus in brain tissue of mink suffering from shaking mink syndrome by use of viral metagenomics. J Clin Microbiol 48:4392–4396 [CrossRef][PubMed]
    [Google Scholar]
  4. Bridger J. C. 1980; Detection by electron microscopy of caliciviruses, astroviruses and rotavirus-like particles in the faeces of piglets with diarrhoea. Vet Rec 107:532–533[PubMed]
    [Google Scholar]
  5. Chu D. K., Poon L. L., Guan Y., Peiris J. S. 2008; Novel astroviruses in insectivorous bats. J Virol 82:9107–9114 [CrossRef][PubMed]
    [Google Scholar]
  6. Decaro N., Pratelli A., Campolo M., Elia G., Martella V., Tempesta M., Buonavoglia C. 2004; Quantitation of canine coronavirus RNA in the faeces of dogs by TaqMan RT-PCR. J Virol Methods 119:145–150 [CrossRef][PubMed]
    [Google Scholar]
  7. Decaro N., Elia G., Martella V., Desario C., Campolo M., Trani L. D., Tarsitano E., Tempesta M., Buonavoglia C. 2005; A real-time PCR assay for rapid detection and quantitation of canine parvovirus type 2 in the feces of dogs. Vet Microbiol 105:19–28 [CrossRef][PubMed]
    [Google Scholar]
  8. Decaro N., Elia G., Campolo M., Desario C., Mari V., Radogna A., Colaianni M. L., Cirone F., Tempesta M., Buonavoglia C. 2008; Detection of bovine coronavirus using a TaqMan-based real-time RT-PCR assay. J Virol Methods 151:167–171 [CrossRef][PubMed]
    [Google Scholar]
  9. Elia G., Decaro N., Martella V., Cirone F., Lucente M. S., Lorusso E., Di Trani L., Buonavoglia C. 2006; Detection of canine distemper virus in dogs by real-time RT-PCR. J Virol Methods 136:171–176 [CrossRef][PubMed]
    [Google Scholar]
  10. Englund L., Chriél M., Dietz H. H., Hedlund K. O. 2002; Astrovirus epidemiologically linked to pre-weaning diarrhoea in mink. Vet Microbiol 85:1–11 [CrossRef][PubMed]
    [Google Scholar]
  11. Evermann J. F., McKeirnan A. J., Smith A. W., Skilling D. E., Ott R. L. 1985; Isolation and identification of caliciviruses from dogs with enteric infections. Am J Vet Res 46:218–220[PubMed]
    [Google Scholar]
  12. Gentsch J. R., Glass R. I., Woods P., Gouvea V., Gorziglia M., Flores J., Das B. K., Bhan M. K. 1992; Identification of group A rotavirus gene 4 types by polymerase chain reaction. J Clin Microbiol 30:1365–1373[PubMed]
    [Google Scholar]
  13. Hall T. A. 1999; BioEdit: a user-friendly biological sequence alignment and analysis program for Windows 95/98/NT. Nucleic Acids Symp Ser 41:95–98
    [Google Scholar]
  14. Hoshino Y., Zimmer J. F., Moise N. S., Scott F. W. 1981; Detection of astroviruses in feces of a cat with diarrhea. Arch Virol 70:373–376 [CrossRef][PubMed]
    [Google Scholar]
  15. Hu R. L., Huang G., Qiu W., Zhong Z. H., Xia X. Z., Yin Z. 2001; Detection and differentiation of CAV-1 and CAV-2 by polymerase chain reaction. Vet Res Commun 25:77–84 [CrossRef][PubMed]
    [Google Scholar]
  16. Imada T., Yamaguchi S., Mase M., Tsukamoto K., Kubo M., Morooka A. 2000; Avian nephritis virus (ANV) as a new member of the family Astroviridae and construction of infectious ANV cDNA. J Virol 74:8487–8493 [CrossRef][PubMed]
    [Google Scholar]
  17. Jonassen C. M., Jonassen T. O., Grinde B. 1998; A common RNA motif in the 3′ end of the genomes of astroviruses, avian infectious bronchitis virus and an equine rhinovirus. J Gen Virol 79:715–718[PubMed]
    [Google Scholar]
  18. Kjeldsberg E., Hem A. 1985; Detection of astroviruses in gut contents of nude and normal mice. Arch Virol 84:135–140 [CrossRef][PubMed]
    [Google Scholar]
  19. Koopmans M. P., Bijen M. H., Monroe S. S., Vinjé J. 1998; Age-stratified seroprevalence of neutralizing antibodies to astrovirus types 1 to 7 in humans in The Netherlands. Clin Diagn Lab Immunol 5:33–37[PubMed]
    [Google Scholar]
  20. Krishna N. K. 2005; Identification of structural domains involved in astrovirus capsid biology. Viral Immunol 18:17–26 [CrossRef][PubMed]
    [Google Scholar]
  21. Kurtz J. B., Lee T. W. 1984; Human astrovirus serotypes. Lancet 324:1405 [CrossRef][PubMed]
    [Google Scholar]
  22. Madeley C. R., Cosgrove B. P. 1975; Letter: 28 nm particles in faeces in infantile gastroenteritis. Lancet 306:451–452 [CrossRef][PubMed]
    [Google Scholar]
  23. Marshall J. A., Healey D. S., Studdert M. J., Scott P. C., Kennett M. L., Ward B. K., Gust I. D. 1984; Viruses and virus-like particles in the faeces of dogs with and without diarrhoea. Aust Vet J 61:33–38 [CrossRef][PubMed]
    [Google Scholar]
  24. Martella V., Lorusso E., Decaro N., Elia G., Radogna A., D’Abramo M., Desario C., Cavalli A., Corrente M. et al. 2008; Detection and molecular characterization of a canine norovirus. Emerg Infect Dis 14:1306–1308 [CrossRef][PubMed]
    [Google Scholar]
  25. Martella V., Decaro N., Lorusso E., Radogna A., Moschidou P., Amorisco F., Lucente M. S., Desario C., Mari V. et al. 2009; Genetic heterogeneity and recombination in canine noroviruses. J Virol 83:11391–11396 [CrossRef][PubMed]
    [Google Scholar]
  26. McNulty M. S., Curran W. L., McFerran J. B. 1980; Detection of astroviruses in turkey faeces by direct electron microscopy. Vet Rec 106:561 [CrossRef][PubMed]
    [Google Scholar]
  27. Méndez E., Arias C. 2007; Astroviruses. In Fields Virology, 5th edn. pp. 981–1000 Edited by Knipe D. M., Howley P. M. Philadelphia: Lippincott Willliams & Wilkins;
    [Google Scholar]
  28. Méndez-Toss M., Romero-Guido P., Munguía M. E., Méndez E., Arias C. F. 2000; Molecular analysis of a serotype 8 human astrovirus genome. J Gen Virol 81:2891–2897[PubMed]
    [Google Scholar]
  29. Mochizuki M., Kawanishi A., Sakamoto H., Tashiro S., Fujimoto R., Ohwaki M. 1993; A calicivirus isolated from a dog with fatal diarrhoea. Vet Rec 132:221–222 [CrossRef][PubMed]
    [Google Scholar]
  30. Pollock R. V. H., Carmichael L. E. 1982; Maternally derived immunity to canine parvovirus infection: transfer, decline, and interference with vaccination. J Am Vet Med Assoc 180:37–42[PubMed]
    [Google Scholar]
  31. Pratelli A., Tempesta M., Roperto F. P., Sagazio P., Carmichael L., Buonavoglia C. 1999; Fatal coronavirus infection in puppies following canine parvovirus 2b infection. J Vet Diagn Invest 11:550–553[PubMed] [CrossRef]
    [Google Scholar]
  32. Rivera R., Nollens H. H., Venn-Watson S., Gulland F. M., Wellehan J. F. Jr 2010; Characterization of phylogenetically diverse astroviruses of marine mammals. J Gen Virol 91:166–173 [CrossRef][PubMed]
    [Google Scholar]
  33. Sanchez-Fauquier A., Carrascosa A. L., Carrascosa J. L., Otero A., Glass R. I., Lopez J. A., San Martin C., Melero J. A. 1994; Characterization of a human astrovirus serotype 2 structural protein (VP26) that contains an epitope involved in virus neutralization. Virology 201:312–320 [CrossRef][PubMed]
    [Google Scholar]
  34. San Gabriel M. C., Tohya Y., Sugimura T., Shimizu T., Ishiguro S., Mochizuki M. 1997; Identification of canine calicivirus capsid protein and its immunoreactivity in Western blotting. J Vet Med Sci 59:97–101 [CrossRef][PubMed]
    [Google Scholar]
  35. Schaffer F. L., Soergel M. E., Black J. W., Skilling D. E., Smith A. W., Cubitt W. D. 1985; Characterization of a new calicivirus isolated from feces of a dog. Arch Virol 84:181–195 [CrossRef][PubMed]
    [Google Scholar]
  36. Snodgrass D. R., Gray E. W. 1977; Detection and transmission of 30 nm virus particles (astroviruses) in faeces of lambs with diarrhoea. Arch Virol 55:287–291 [CrossRef][PubMed]
    [Google Scholar]
  37. Tamura K., Dudley J., Nei M., Kumar S. 2007; mega4: Molecular Evolutionary Genetics Analysis (mega) software version 4.0. Mol Biol Evol 24:1596–1599 [CrossRef][PubMed]
    [Google Scholar]
  38. Todd D., Smyth V. J., Ball N. W., Donnelly B. M., Wylie M., Knowles N. J., Adair B. M. 2009; Identification of chicken enterovirus-like viruses, duck hepatitis virus type 2 and duck hepatitis virus type 3 as astroviruses. Avian Pathol 38:21–30 [CrossRef][PubMed]
    [Google Scholar]
  39. Toffan A., Jonassen C. M., De Battisti C., Schiavon E., Kofstad T., Capua I., Cattoli G. 2009; Genetic characterization of a new astrovirus detected in dogs suffering from diarrhoea. Vet Microbiol 139:147–152 [CrossRef][PubMed]
    [Google Scholar]
  40. Tzipori S., Menzies J. D., Gray E. W. 1981; Detection of astrovirus in the faeces of red deer. Vet Rec 108:286 [CrossRef][PubMed]
    [Google Scholar]
  41. Vennema H., de Bruin E., Koopmans M. 2002; Rational optimization of generic primers used for Norwalk-like virus detection by reverse transcriptase polymerase chain reaction. J Clin Virol 25:233–235 [CrossRef][PubMed]
    [Google Scholar]
  42. Vieler E., Herbst W. 1995; [Electron microscopic demonstration of viruses in feces of dogs with diarrhea]. Tierarztl Prax 23:66–69 (in German) [PubMed]
    [Google Scholar]
  43. Walter J. E., Briggs J., Guerrero M. L., Matson D. O., Pickering L. K., Ruiz-Palacios G., Berke T., Mitchell D. K. 2001; Molecular characterization of a novel recombinant strain of human astrovirus associated with gastroenteritis in children. Arch Virol 146:2357–2367 [CrossRef][PubMed]
    [Google Scholar]
  44. Wang Q. H., Han M. G., Cheetham S., Souza M., Funk J. A., Saif L. J. 2005; Porcine noroviruses related to human noroviruses. Emerg Infect Dis 11:1874–1881[PubMed] [CrossRef]
    [Google Scholar]
  45. Williams F. P. Jr 1980; Astrovirus-like, coronavirus-like, and parvovirus-like particles detected in the diarrheal stools of beagle pups. Arch Virol 66:215–226 [CrossRef][PubMed]
    [Google Scholar]
  46. Woode G. N., Bridger J. C. 1978; Isolation of small viruses resembling astroviruses and caliciviruses from acute enteritis of calves. J Med Microbiol 11:441–452 [CrossRef][PubMed]
    [Google Scholar]
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