1887

Abstract

The susceptibility of chickens to both 1918 and 2009 H1N1 influenza virus was evaluated. The intravenous pathogenicity index of 1918 and 2009 H1N1 viruses in chickens was 0. Chickens did not develop clinical signs following experimental inoculation simulating natural infection. No gross pathological changes were observed in any tissues of chickens between 2 and 18 days post-infection (p.i.) and viral RNA was not detected by real-time RT-PCR in mucosal secretions or tissues. Seroconversion was not detected in any of the chickens following inoculation with H1N1 2009 virus, whereas half the chickens developed influenza-specific antibodies at 28 days p.i. with 1918 influenza, suggesting limited infection. Viral RNA was detected by real-time RT-PCR in mallard ducks following inoculation with 1918 influenza virus at 3 days p.i. in cloacal swabs, but not in tissues, and all ducks seroconverted by 28 days p.i. Both 1918 and 2009 H1N1 influenza viruses behave as LPAI in gallinaceous poultry.

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2010-02-01
2019-11-21
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