1887

Abstract

Astroviruses infect humans and many different animal species and are associated with gastroenteritis. Recent studies first detected the virus from bat species in Hong Kong. To understand astrovirus distribution in the wider region further, we examined the prevalence of this virus family in bat specimens collected from a large geographical region of mainland China. We collected 500 anal swabs from 20 bat species in 51 natural habitats from 11 provinces of China and tested these for astroviruses. Our study revealed a remarkably high genetic diversity of astroviruses; five monophyletic groups were identified in bats, including two novel groups. Evidence for varying degrees of host restriction for astroviruses from bats has been found. Phylogenetic analyses also provided insight into the inter-species transmission of Mamastrovirus.

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2009-04-01
2024-11-04
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References

  1. Bininda-Emonds O. R. P. 2005; transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences. BMC Bioinformatics 6:156 [CrossRef]
    [Google Scholar]
  2. Chu D. K. W., Poon L. L. M., Guan Y., Peiris J. S. M. 2008; Novel astroviruses in insectivorous bats. J Virol 82:9107–9114 [CrossRef]
    [Google Scholar]
  3. Guan Y., Zheng B. J., He Y. Q., Liu X. L., Zhuang Z. X., Cheung C. L., Luo S. W., Li P. H., Zhang L. J. other authors 2003; Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China. Science 302:276–278 [CrossRef]
    [Google Scholar]
  4. Herrmann J. E., Taylor D. N., Echeverria P., Blacklow N. R. 1991; Astroviruses as a cause of gastroenteritis in children. N Engl J Med 324:1757–1760 [CrossRef]
    [Google Scholar]
  5. Holmes E. C., Rambaut A. 2004; Viral evolution and the emergence of SARS coronavirus. Philos Trans R Soc Lond B Biol Sci 359:1059–1065 [CrossRef]
    [Google Scholar]
  6. Huelsenbeck J. P., Ronquist F. 2001; MrBayes: Bayesian inference of phylogenetic trees. Bioinformatics 17:754–755 [CrossRef]
    [Google Scholar]
  7. Kosakovsky Pond S. L., Posada D., Gravenor M. B., Woelk C. H., Frost S. D. W. 2006; Automated phylogenetic detection of recombination using a genetic algorithm. Mol Biol Evol 23:1891–1901 [CrossRef]
    [Google Scholar]
  8. Méndez E., Arias C. F. 2007; Astroviruses. In Fields Virology , 5th edn. pp 981–1000Edited by Knipe D. M., Howley P. M., Griffin D. E., Lamb R. A., Martin M. A., Roizman B., Straus. Philadelphia, PA: Lippincott, Williams & Wilkins;
    [Google Scholar]
  9. Moya A., Holmes E. C., González-Candelas F. 2004; The population genetics and evolutionary epidemiology of RNA viruses. Nat Rev Microbiol 2:279–288 [CrossRef]
    [Google Scholar]
  10. Posada D., Crandall K. A. 1998; modeltest: testing the model of DNA substitution. Bioinformatics 14:817–818 [CrossRef]
    [Google Scholar]
  11. Reynolds D. L., Saif Y. M. 1986; Astrovirus: a cause of an enteric disease in turkey poults. Avian Dis 30:728–735 [CrossRef]
    [Google Scholar]
  12. Shimizu M., Shirai J., Narita M., Yamane T. 1990; Cytopathic astrovirus isolated from porcine acute gastroenteritis in an established cell line derived from porcine embryonic kidney. J Clin Microbiol 28:201–206
    [Google Scholar]
  13. Snodgrass D. R., Gray E. W. 1977; Detection and transmission of 30 nm virus particles (astroviruses) in faeces of lambs with diarrhoea. Arch Virol 55:287–291 [CrossRef]
    [Google Scholar]
  14. Strain E., Kelley L. A., Schultz-Cherry S., Muse S. V., Koci M. D. 2008; Genomic analysis of closely related astroviruses. J Virol 82:5099–5103 [CrossRef]
    [Google Scholar]
  15. Tang X. C., Zhang J. X., Zhang S. Y., Wang P., Fan X. H., Li L. F., Li G., Dong B. Q., Liu W. other authors 2006; Prevalence and genetic diversity of coronaviruses in bats from China. J Virol 80:7481–7490 [CrossRef]
    [Google Scholar]
  16. Thompson J. D., Higgins D. G., Gibson T. J. 1994; clustal w: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22:4673–4680 [CrossRef]
    [Google Scholar]
  17. Vijaykrishna D., Smith G. J. D., Zhang J. X., Peiris J. S. M., Chen H., Guan Y. 2007; Evolutionary insights into the ecology of coronaviruses. J Virol 81:4012–4020 [CrossRef]
    [Google Scholar]
  18. Zwickl D. 2006; Genetic algorithm approaches for the phylogenetic analysis of large biological sequence datasets under the maximum likelihood criterion . PhD thesis University of Texas at Austin;
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